<![CDATA[Newsroom University of Manchester]]> /about/news/ en Sat, 02 Aug 2025 01:12:01 +0200 Fri, 01 Aug 2025 12:56:36 +0200 <![CDATA[Newsroom University of Manchester]]> https://content.presspage.com/clients/150_1369.jpg /about/news/ 144 Manchester scientists achieve brain-like memory in nanofluidic devices /about/news/manchester-scientists-achieve-brain-like-memory-in-nanofluidic-devices/ /about/news/manchester-scientists-achieve-brain-like-memory-in-nanofluidic-devices/716009Researchers at ֱ’s National Graphene Institute have developed a new class of programmable nanofluidic memristors that mimic the memory functions of the human brain, paving the way for next-generation neuromorphic computing.

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Programmable 2D nanochannels mimic both synaptic behaviour and multiple memory types, marking a major advance in neuromorphic computing.

 

Researchers at ֱ’s have developed a new class of programmable nanofluidic memristors that mimic the memory functions of the human brain, paving the way for next-generation neuromorphic computing.

In a ground-breaking study published in , scientists from the , and the have demonstrated how two-dimensional (2D) nanochannels can be tuned to exhibit all four theoretically predicted types of memristive behaviour, something never before achieved in a single device. This study not only reveals new insights into ionic memory mechanisms but also has the potential to enable emerging applications in low-power ionic logic, neuromorphic components, and adaptive chemical sensing.

Memristors, or memory resistors, are components that adjust their resistance based on past electrical activity, effectively storing a memory of it. While most existing memristors are solid-state devices that rely on electron movement, the team, led by Prof Radha Boya, used confined liquid electrolytes within thin nanochannels made from 2D materials like MoS₂ and hBN. This nanofluidic approach allows for ultra-low energy operation and the ability to emulate biological learning processes.

 

Four memory modes, one device

The study reveals that by tuning experimental parameters such as electrolyte composition, pH, voltage frequency, and channel geometry, the same nanofluidic device can switch between four distinct memory loop styles, two “crossing” and two “non-crossing” types. These loop styles correspond to different memory mechanisms, including ion-ion interaction, ion-surface charge adsorption/desorption, surface charge inversion, and ion concentration polarisation.

“This is the first time all four memristor types have been observed in a single device,” said , senior author of the study. “It shows the remarkable tunability of nanofluidic systems and their potential to replicate complex brain-like behaviour.”

 

Mimicking the brain’s synapses

Beyond demonstrating multiple memory modes, the devices also exhibit both short-term and long-term memory, akin to biological synapses. This dynamic control over memory duration is crucial for developing neuromorphic systems that can adapt and learn from their environment.

brain-like memory in nanofluidic devices

For instance, the devices could “forget” information over time or retain it for days, depending on the applied voltage and electrolyte conditions, e.g., like how one might quickly forget where they left their keys, yet remember their home address for life.

Imagine you're working in a café. At first, the clatter of cups and chatter is noticeable, but soon your brain filters it out so you can focus. This everyday phenomenon is called sensory adaptation, and short-term synaptic depression is one of the cellular mechanisms contributing to them. The team mimicked short-term synaptic depression, a process where consecutive neural signals reduce the strength of a response unless sufficient time is allowed for recovery. In neurons, this is caused by temporary depletion of neurotransmitter vesicles. In the nanochannels, a similar effect emerges due to the ionic interactions, which requires time to relax back to its initial state.

 

A minimal model and a major leap

To explain the observed behaviours, the team developed a minimal theoretical model that incorporates ion–ion interactions, surface adsorption, and channel entrance effects. The model successfully reproduces all four memristive loop types, offering a unified framework for understanding and designing future nanofluidic memory systems.

“This work represents a major leap in our understanding of ionic memory,” said Dr Abdulghani Ismail, lead author of the study. “It opens up exciting possibilities for low-power, adaptive computing systems that operate more like the human brain.”

 

Towards brain-inspired computing

By harnessing the unique properties of 2D materials and fluidic ion transport, the researchers envision a new class of reconfigurable, energy-efficient computing devices capable of real-time learning and decision-making, with broad implications for artificial intelligence, robotics, and bioelectronics.

 

This research was published in the journal .

Full title: Programmable memristors with two-dimensional nanofluidic channels

DOI: 10.1038/s41467-025-61649-6

 

The is a world-leading graphene and 2D material centre, focussed on fundamental research. Based at ֱ, where graphene was first isolated in 2004 by Professors Sir Andre Geim and Sir Kostya Novoselov, it is home to leaders in their field – a community of research specialists delivering transformative discovery. This expertise is matched by £13m leading-edge facilities, such as the largest class 5 and 6 cleanrooms in global academia, which gives the NGI the capabilities to advance underpinning industrial applications in key areas including: composites, functional membranes, energy, membranes for green hydrogen, ultra-high vacuum 2D materials, nanomedicine, 2D based printed electronics, and characterisation.

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Fri, 01 Aug 2025 13:00:00 +0100 https://content.presspage.com/uploads/1369/12ad6712-83de-4800-a802-d7cf7b48d227/500_picture2-3.jpg?10000 https://content.presspage.com/uploads/1369/12ad6712-83de-4800-a802-d7cf7b48d227/picture2-3.jpg?10000
Manchester researchers design electric thermal switch for space applications /about/news/manchester-researchers-design-electric-thermal-switch-for-space-applications/ /about/news/manchester-researchers-design-electric-thermal-switch-for-space-applications/714234An international team led by researchers at ֱ’s has demonstrated a ground-breaking device capable of electrically controlling heat flow, potentially transforming thermal management in aerospace and advanced electronic applications. The findings are detailed in their recent publication in .

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An international team led by researchers at ֱ’s has demonstrated a ground-breaking device capable of electrically controlling heat flow, potentially transforming thermal management in aerospace and advanced electronic applications. The findings are detailed in their recent publication in .

The team introduced a new type of thermal switch utilising high thermal conductivity graphite films. When a voltage is applied, ions insert between graphite layers. These ions disrupt phonon motion, cutting thermal conductivity by up to 1,300%. Removing the voltage expels the ions and restores the original heat-carrying capacity. This powerful modulation allows the device to actively turn heat conduction "on" and "off" at will, mirroring the functionality of electronic transistors, but for heat instead of electricity.

 “What makes our device truly transformative is its ability to operate reliably in extreme environments such as space,” said Dr Pietro Steiner, lead author and current technology lead for graphene-based thermal technologies at , a spinout from the University of Manchester. "The solid-state nature and absence of mechanical parts make it particularly attractive for aerospace applications, where reliability, weight, and efficiency are critical."

Beyond basic switching, the team demonstrated that their device could actively steer heat flow in desired directions. By configuring voltages across patterned electrodes, they created anisotropic thermal conduction pathways, opening possibilities for programmable thermal management systems.

Lead author added, "This thermal switching technology could revolutionise spacecraft thermal regulation, offering dynamic and reconfigurable solutions to manage excess heat without complex moving mechanisms or bulky radiators."

Spacecraft often rely on radiators or mechanical valves to dump excess heat. These systems add weight and risk mechanical failure under vibration. A thin, solid-state switch removes those constraints. It can operate in ultra-high vacuum and tolerate radiation levels found in orbit.

Next, the group will test switching speed under high thermal load. They plan to integrate the switch with prototype electronics. Faster ion motion and alternative intercalants could boost performance further. By directly linking electrical signals to heat transport, this work lays the groundwork for programmable thermal management in aerospace, electronics cooling and adaptive insulation.

 

This research was published in the journal .

Full title: Electrically controlled heat transport in graphite films via reversible ionic liquid intercalation

DOI: 10.1126/sciadv.adw8588

 

The is a world-leading graphene and 2D material centre, focussed on fundamental research. Based at ֱ, where graphene was first isolated in 2004 by Professors Sir Andre Geim and Sir Kostya Novoselov, it is home to leaders in their field – a community of research specialists delivering transformative discovery. This expertise is matched by £13m leading-edge facilities, such as the largest class 5 and 6 cleanrooms in global academia, which gives the NGI the capabilities to advance underpinning industrial applications in key areas including: composites, functional membranes, energy, membranes for green hydrogen, ultra-high vacuum 2D materials, nanomedicine, 2D based printed electronics, and characterisation.

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Tue, 29 Jul 2025 07:30:00 +0100 https://content.presspage.com/uploads/1369/5c65ae20-65c6-482e-b45a-a8b3c21bcd5a/500_thermalswitch.jpg?10000 https://content.presspage.com/uploads/1369/5c65ae20-65c6-482e-b45a-a8b3c21bcd5a/thermalswitch.jpg?10000
Graphene-silver coating promises long-term defence against bacteria /about/news/manchester-team-pioneer-silver-based-coating-for-long-term-protection-against-bacteria/ /about/news/manchester-team-pioneer-silver-based-coating-for-long-term-protection-against-bacteria/715449Researchers at the have developed a new type of antimicrobial coating that could improve hygiene across healthcare, consumer, and industrial products. Working in partnership with medical technology company Smith & Nephew, the team, led by Prof Rahul R Nair, has published its findings in the journal .

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Researchers at the have developed a new type of antimicrobial coating that could improve hygiene across healthcare, consumer, and industrial products. Working in partnership with medical technology company Smith & Nephew, the team, led by Prof Rahul R Nair, has published its findings in the journal .

Silver has long been used to combat bacteria, particularly in wound care, due to its ability to release ions that disrupt bacterial cells. However, current approaches have limitations; silver can be released too rapidly or unevenly, potentially harming surrounding healthy tissue and resulting in short-lived or inconsistent antibacterial protection.

The Manchester team tackled these issues by designing a graphene oxide-based membrane that can release silver ions slowly and precisely over time. The key lies in the structure of the membrane itself, its nanoscale channels act like filters, regulating how much silver is released.

"Our research represents a paradigm shift in antimicrobial coating technology," states lead author . "By harnessing the potential of graphene oxide membranes, we've unlocked a method for controlled silver ion release, paving the way for sustained antimicrobial efficacy in various applications.”

The team also created a testing model that better reflects real biological conditions. By using foetal bovine serum in lab trials, they could simulate the environment the coating would encounter in the body, offering a clearer view of how it performs over time.

“This approach allows us to deliver just the right amount of silver for extended protection,” first author Dr Swathi Suran adds. “It has potential in many areas, including wound care dressings and antimicrobial coatings for implants, and could bring long-term benefits for both patients and healthcare providers.”

As the team looks ahead, they're focused on exploring how this coating could be integrated into a range of everyday and medical products, making bacterial resistance less of a hidden threat and more of a manageable challenge.

 

This research was published in the journal .

Full title: Tunable Release of Ions from Graphene Oxide Laminates for Sustained Antibacterial Activity in a Biomimetic Environment

DOI:

 

The National Graphene Institute (NGI) is a world-leading graphene and 2D material centre, focussed on fundamental research. Based at ֱ, where graphene was first isolated in 2004 by Professors Sir Andre Geim and Sir Kostya Novoselov, it is home to leaders in their field – a community of research specialists delivering transformative discovery. This expertise is matched by £13m leading-edge facilities, such as the largest class 5 and 6 cleanrooms in global academia, which gives the NGI the capabilities to advance underpinning industrial applications in key areas including: composites, functional membranes, energy, membranes for green hydrogen, ultra-high vacuum 2D materials, nanomedicine, 2D based printed electronics, and characterisation.

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Mon, 28 Jul 2025 10:00:00 +0100 https://content.presspage.com/uploads/1369/943f6090-271a-4be9-b0ee-0ca286d94c3c/500_169.jpg?10000 https://content.presspage.com/uploads/1369/943f6090-271a-4be9-b0ee-0ca286d94c3c/169.jpg?10000
Manchester scientists discover new light behaviour in common mineral gypsum /about/news/manchester-scientists-discover-new-light-behaviour-in-common-mineral-gypsum/ /about/news/manchester-scientists-discover-new-light-behaviour-in-common-mineral-gypsum/714646A new study published in Science Advances by researchers from the at University of Manchester and the University of Oviedo, has revealed a previously unseen behaviour of light in gypsum, a mineral better known for its use in building plaster and chalk.

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A new study published in by researchers from the at University of Manchester and the University of Oviedo, has revealed a previously unseen behaviour of light in gypsum, a mineral better known for its use in building plaster and chalk.

The team uncovered a rare type of wave, known as a shear phonon polariton, in a two-dimensional form of the material. Phonon polaritons are light-matter hybrid waves that emerge when light interacts with atomic vibrations in certain crystals. They can travel through materials in unusual ways and concentrate light into extremely small volumes.

In this study, the researchers found that in  thin films of gypsum, these waves undergo a topological transition, shifting from hyperbolic to elliptical behaviour, passing through a unique canalized state.

This transition allows scientists to tune how light propagates through the material.

“The studies of shear phonon polaritons in previous studies were limited to bulk crystals in the hyperbolic regime. In our study we aimed to complement those initial findings with shear polaritons in a 2-dimentional material,” said Dr Pablo Díaz Núñez, who co-led the study. “And remarkably, we discovered that shear phonon polaritons in gypsum support a topological transition from hyperbolic to elliptical propagation, with canalization in between.”

Dr Díaz Núñez added, “Moreover, we were able to confine light to a space twenty-five times smaller than its wavelength and slow it down to just a fraction of its speed in vacuum, this opens up new possibilities for manipulating light at the nanoscale.”

The research also highlights the role of crystal symmetry. Gypsum belongs to a class of materials with low symmetry, specifically to the monoclinic crystal system, which gives rise to asymmetric light propagation and energy loss, the central characteristic of shear polaritons.

These findings extend beyond fundamental research of phonon polariton propagation and could support future developments in areas that rely on precise control of light, such as thermal management, sensing, and imaging beyond the limits of conventional optics. Moreover, the study introduces gypsum as a new platform for exploring advanced photonic concepts in emerging areas like non-Hermitian photonics.

 

This research was published in the journal .

Full title: Visualization of topological shear polaritons in gypsum thin films

DOI:

 

The National Graphene Institute (NGI) is a world-leading graphene and 2D material centre, focussed on fundamental research. Based at ֱ, where graphene was first isolated in 2004 by Professors Sir Andre Geim and Sir Kostya Novoselov, it is home to leaders in their field – a community of research specialists delivering transformative discovery. This expertise is matched by £13m leading-edge facilities, such as the largest class 5 and 6 cleanrooms in global academia, which gives the NGI the capabilities to advance underpinning industrial applications in key areas including: composites, functional membranes, energy, membranes for green hydrogen, ultra-high vacuum 2D materials, nanomedicine, 2D based printed electronics, and characterisation.

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Mon, 21 Jul 2025 13:18:35 +0100 https://content.presspage.com/uploads/1369/0ef18bf1-ca0b-416d-b190-1c601ba2c6b3/500_lightbehaviouringypsum.png?10000 https://content.presspage.com/uploads/1369/0ef18bf1-ca0b-416d-b190-1c601ba2c6b3/lightbehaviouringypsum.png?10000
Early Career Researchers secure funding through the Researcher to Innovator (R2I) programme to support the commercial development of their ideas /about/news/early-career-researchers-secure-funding-through-the-researcher-to-innovator-r2i-programme-to-support-the-commercial-development-of-their-ideas/ /about/news/early-career-researchers-secure-funding-through-the-researcher-to-innovator-r2i-programme-to-support-the-commercial-development-of-their-ideas/715002Twenty-four early career researchers have successfully completed the MEC Researcher to Innovator (R2I) programme.

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Twenty-four early career researchers have now successfully completed the MEC Researcher to Innovator (R2I) programme, an exciting entrepreneurship training programme for researchers with ambitions to develop commercial ventures and create impact from their research.

On Thursday 17th July 2025, researchers from ֱ furthered their entrepreneurial journey by completing the MEC R2I programme at the Options Roundabout event. The event saw participants pitch their innovations to a panel of commercialisation experts, entrepreneurs and funders from across the University. The day concluded with a celebration of the cohort’s accomplishments with peers and supporters of the programme, as well as a networking opportunity to aid them in their next steps.

The R2I programme aims to inspire and accelerate the translation of academic research into impact-driven ventures. Over the course of 12-weeks, participants benefited from a series of bespoke workshops and mentoring opportunities to help them articulate their ideas and explore the commercial potential of their research.

Six Innovation Enabling Awards were granted to acknowledge the progress and growth potential, with early career researchers receiving between £2,000 to £10,000 to support the further development of their businesses.

Aurore Hochard, Director of the Masood Entrepreneurship Centre, presented the Innovation Enabling Awards to the six winning projects.

Award Winners

Innovation Enabling Award: £10,000

3. 2J3A4092 - Cropped_Abby

Lutèo Medical

Dr Abigail Elias (School of Biological Sciences)

The support, mentoring, and resources provided through the Researcher to Innovator (R2I) programme have been transformative. Most importantly, the experience gave me the confidence to reach out to potential stakeholders and begin building the connections needed to bring my ideas to life. It was also great to connect with people on the cohort from such a broad range of disciplines."

 

Innovation Enabling Award: £5,0004. 2J3A4086 - Cropped_Daniel

ViRTUE: Virtual Reality Training in Ultrasonic Evaluation

Daniel Conniffe (School of Engineering)

“R2I equipped me with the resources, motivation, and communication skills to bridge the gap between research and industry. Through building a strong network, I gained insight into real-world challenges and was able to pivot my research toward creating a meaningful, practical solution.”

 

Innovation Enabling Award: £3,000

5. 2J3A4085 - Cropped_Premlal

Hollowgraf

Dr Premlal Balakrishna Pillai (School of Engineering)

“The encouragement, guidance, and practical knowledge I gained through R2I have been truly inspiring. The programme really helped me to clarify my idea and shape it into a commercially viable opportunity, giving me the confidence to take the first steps into entrepreneurship.”

 

 

Innovation Enabling Award: £2,000

6. 2J3A4079 - Cropped_Sergio

PRECIOUS: Programmable Recovery of Critical Elements Using Synthetic Biology

Dr Sergio Gutiérrez Zapata (School of Natural Sciences)

“The R2I programme gave me the push I didn’t know I needed. It helped me go from a scientific idea to something that could actually work in the real world — with real people and real challenges. Being able to shape a venture around bioremediation, and test the idea from different angles, has been incredibly motivating.”

 

Innovation Enabling Award: £2,000

7. 2J3A4075 - Cropped_Dougal

 

PRISM: Prostate cancer Risk Identification by Spectroscopic Measurement

Dr Dougal Ferguson (School of Engineering)

The R2I programme really helped me hone my ability to concisely and impactfully pitch my research as a commercial application. I am much more confident now pitching my science to a non-scientific audience!”

 

 

Innovation Enabling Award: £2,000

8. 2J3A4081 - Cropped_Yoana

Inclusive Skincare Solutions

Yoana Kirilova (School of Biological Sciences)

“The Researcher to Innovator programme has been a fantastic journey – connecting with like-minded peers, learning from experienced entrepreneurs, and gaining insights that will continue to shape my innovation journey.”

 

 

The prize winners will also receive expert support and signposting to regional and national accelerator programmes and all the participants on the MEC R2I programme will be connected to the wider ecosystem for further support, mentoring and guidance in taking their research ideas forward.

The organisers wish to thank the Innovation Academy and the Engineers for Business Fellowship for their sponsorship of the Innovation Enabling Awards.

EIBF logo standard

The  is supported by the University’s Innovation Academy. The Innovation Academy is a pan University initiative and joint venture between the , the  and the Business Engagement and Knowledge Exchange team, bringing together knowledge, expertise and routes to facilitate the commercialisation of research.

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Fri, 18 Jul 2025 14:03:00 +0100 https://content.presspage.com/uploads/1369/e8a60e3e-8dc9-4c0a-9171-31185d3b9b0f/500_1.2j3a4113-group.jpg?10000 https://content.presspage.com/uploads/1369/e8a60e3e-8dc9-4c0a-9171-31185d3b9b0f/1.2j3a4113-group.jpg?10000
New study reveals the hidden forces behind Alpine debris flows, boosting future protection /about/news/new-study-reveals-the-hidden-forces-behind-alpine-debris-flows-boosting-future-protection/ /about/news/new-study-reveals-the-hidden-forces-behind-alpine-debris-flows-boosting-future-protection/714352New research provides unprecedented insights into the hidden forces behind devastating Alpine debris flows, offering hope for better protection against future disasters.

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New research provides unprecedented insights into the hidden forces behind devastating Alpine debris flows, offering hope for better protection against future disasters.

The study, led by ETH Zurich and supported by ֱ, sheds new light on how fast-moving mixtures of water, soil and rocks – known as debris flows – develop into a series of surges, destroying everything in their path. 

Using highly sensitive 3D laser scanners, the scientists collected measurements during a major debris flow in the Illgraben valley in Switzerland on 5 June 2022. Analysis enabled the scientists to pinpoint how small surface disturbances evolve down the channel into powerful large amplitude waves that concentrate the flow’s destructive power.

The findings, published in the journal , are among the most detailed measurements of a real-life debris flow ever recorded.

Debris flows are a recurring natural hazard in steep terrain throughout the world, and are triggered by heavy rainfall, and increasingly, glacial runoff and permafrost melt. Recent landslides in the Alps continue to highlight the risks posed by debris flows, such as the 2017 Bondo landslide in Graubünden, which triggered a debris flow that travelled 4km downhill into the Bondasca Valley. This emphasises the urgent need to better understand and predict these hazardous events.

Due to the frequency of debris flow occurence, the Illgraben valley has been equipped with measuring instruments since 2000. It has recently supplemented by five highly sensitive 3D laser scanners, called LiDAR, which can determine distance and speed, and six high-speed video cameras.

On the day of the June 2022 event, 25,000 cubic meters of water, earth and debris poured approximately seven kilometres down the bed of the Illbach before the muddy stream was absorbed by the river Rhône at Susten. The devices measured surface velocities and the evolving free surface of the debris flow at three measuring stations with a spatial resolution of 2 cm and a temporal resolution of 0.1 seconds.

The team of scientists from ETH Zurich, Swiss Federal Institute for Forest, Snow and Landscape Research (Birmensdorf) and ֱ, were able to document how the waves grew along the channel and use the data to develop a new friction law that was used in a debris-flow model to realistically simulate the  genesis and growth of the waves.

They found that near the top of the (about 2km from the outflow into the Rhône river), the debris flow had a fast-moving wave front, but no surges, while further down the channel the flow became shallower and spontaneously developed a series of waves. During the 30-minute event, researchers recorded 70 of these surges, which emerge from a surface instability that allows the waves to grow and as they move downhill.

Lead researcher, Jordan Aaron, Professor of Engineering Geology at ETH Zurich, said: "It has long been known that waves play a central role in the destructive power of debris flows, because they concentrate the forces that are applied to structures in their path.

"Thanks to the measurements around the debris flow of June 2022 and the modelling based on them, the researchers now have a better understanding. Our analysis provides new insights into the dynamics of debris flows and enables improved hazard management in the medium term.”

This research, which was partially funded by the UK’s Natural Environment Research Council (), has been published in the journal Communication Earth & Environment

Full title: Detailed observations reveal the genesis and dynamics of destructive debris-flow surges

DOI: doi.org/10.1038/s43247-025-02488-7

Link:  https://www.nature.com/articles/s43247-025-02488-7

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Thu, 17 Jul 2025 12:47:30 +0100 https://content.presspage.com/uploads/1369/bf5407a8-1cf6-4db6-a4e9-7c78b440e523/500_mudslide2.jpg?10000 https://content.presspage.com/uploads/1369/bf5407a8-1cf6-4db6-a4e9-7c78b440e523/mudslide2.jpg?10000
Fossil discovery reveals ancient giant marine reptile relied on stealth while hunting in darkness /about/news/fossil-discovery-reveals-ancient-giant-marine-reptile-relied-on-stealth-while-hunting-in-darkness/ /about/news/fossil-discovery-reveals-ancient-giant-marine-reptile-relied-on-stealth-while-hunting-in-darkness/714236A new study has uncovered evidence that a giant marine reptile from the Early Jurassic period used stealth to hunt its prey in deep or dark waters – much like owls on land today.

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 A new study has uncovered evidence that a giant marine reptile from the Early Jurassic period used stealth to hunt its prey in deep or dark waters – much like owls on land today.

The research, published today in , investigates a meter-long flipper from a Temnodontosaurus - a giant ichthyosaur – with uniquely preserved with fossilised soft tissues.

The findings reveal that the marine reptile, which exceeds 10m in length, was equipped with evolved to have specialised fins that the scientists believe served to suppress the sound of its own movements when foraging in dimly lit environments about 183 million years ago - an evolutionary adaptation never previously seen in any aquatic creature, living or extinct.

The team involves an international team of scientists, led by Dr Johan Lindgren from Lund University in Sweden, in collaboration with one of the world’s leading ichthyosaur experts, , a Palaeontologist at ֱ, who has been working on the fossil for about six years and says the finding “represents one of the greatest fossil discoveries ever made”  and could revolutionise the way scientists investigate other prehistoric animals.

Dr Lindgren, who has pioneered research on ancient marine reptile soft tissues, said: “The wing-like shape of the flipper, together with the lack of bones in the distal end and distinctly serrated trailing edge collectively indicate that this massive animal had evolved means to minimise sound production during swimming. Accordingly, this ichthyosaur must have moved almost silently through the water, in a manner similar to how living owls—whose wing feathers also form a zigzag pattern—fly quietly when hunting at night. We have never seen such elaborate evolutionary adaptations in a marine animal before.”

Although many small ichthyosaurs have been found with soft-tissue preservation, scientists have never found anything on this scale.

Using a range of advanced imaging, chemical analysis and computational modelling techniques, the researchers also identified that the structure of the flippers were truly unique, with scalloped trailing edge reinforced by mineralised, rod-like structures that the team name ‘chondroderms’. 

Moreover, Temnodontosaurus also had the largest eyes – the size of footballs – of any vertebrate known, supporting the hypothesis that this aquatic reptile hunted under low-light conditions, either at night or in deep waters. 

Dr Dean Lomax, who is also an 1851 Research Fellow at the University of Bristol, said: “The first time I saw the specimen, I knew it was unique. Having examined thousands of ichthyosaurs, I had never seen anything quite like it. This discovery will revolutionise the way we look at and reconstruct ichthyosaurs (and possibly also other ancient marine reptiles) but specifically soft-tissue structures in prehistoric animals.”

 The fossilised flipper was discovered by fossil collector Georg Göltz, a co-author on the new study. Remarkably, Georg made the find entirely by chance whilst looking for fossils at a temporary exposure at a road cutting in the municipality of Dotternhausen, Germany.

The fossil consists of both the part and counterpart (opposing sides) of almost an entire front flipper. Although Georg looked for more, no other remains were found. As the top part of the fin is missing, the team surmise that it was originally an isolated flipper that might have been ripped off by a larger ichthyosaur.

Georg brought the specimen to the attention of palaeontologist and co-author Sven Sachs of the Natural History Museum, Bielefeld, who recognised the rarity of the find.

Dr Lindgren said: “The fact that we are able to reconstruct the stealth capabilities of a long-extinct animal is quite remarkable. Also, because human-induced noise from shipping activity, military sonar, seismic surveys, and offshore wind farms has a negative impact on today’s aquatic life, our findings could provide inspiration to help limit the adverse biological effects from anthropogenic input to the modern marine soundscape.”

 To unravel the mystery behind the features preserved in this fossil, it was subjected to a range of sensitive imaging, elemental and molecular analyses. The multidisciplinary research team included palaeontologists, engineers, biologists and physicists. This involved high-end techniques such as synchrotron radiation-based X-ray microtomography at the Swiss Light Source SLS at PSI and Diamond Light Source, time-of-flight secondary ion mass spectrometry and infrared microspectroscopy, along with the reconstruction of a virtual model using computational fluid dynamics.

Dr Lomax added: “The fossil provides new information on the flipper soft tissues of this enormous leviathan, has structures never seen in any animal, and reveals a unique hunting strategy (thus providing evidence of its behaviour), all combined with the fact that its noise-reducing features may even help us to reduce human-made noise pollution. Although I might be a little bias, in my opinion, this represents one of the greatest fossil discoveries ever made.”

The very first ichthyosaur brought to the attention of science was discovered over 200 years ago by pioneering palaeontologist Mary Anning and her brother Joseph. That fossil was also a Temnodontosaurus, the same type of ichthyosaur to which this flipper belonged.

“In a weird way, I feel that there is a wonderful full-circle moment that goes back to Mary Anning showcasing that even after 200 years, we are still uncovering exciting and surprising finds that link back to her initial discoveries”, added Dr Lomax.

Nature article reference: Lindgren, J., Lomax, D. R., Szász, R-Z., Marx, M., Revstedt, J., Göltz, G., Sachs, S., De La Garza, R. G., Heingård, M., Jarenmark, M., Ydström, K., Sjövall, P., Osbæck, F., Hall, S. A., de Beeck, M. O., Eriksson, M. E., Alwmark, C., Marone, F., Liptak, A., Atwood, R., Burca, G., Uvdal, P., Persson, P. and Nilsson, D-E. 2025. Adaptations for stealth in the wing-like flippers of a large ichthyosaur. Nature, 10.1038/s41586-025-09271-w.

Link to paper:

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Wed, 16 Jul 2025 16:00:00 +0100 https://content.presspage.com/uploads/1369/9c0e29ff-126c-4c3e-82b2-1c1e13ce3490/500_image5-3.jpg?10000 https://content.presspage.com/uploads/1369/9c0e29ff-126c-4c3e-82b2-1c1e13ce3490/image5-3.jpg?10000
Skin swabs could detect Parkinson’s disease up to seven years before symptoms appear /about/news/skin-swabs-could-detect-parkinsons-disease-up-to-seven-years-before-symptoms-appear/ /about/news/skin-swabs-could-detect-parkinsons-disease-up-to-seven-years-before-symptoms-appear/714082A new study has revealed promising progress in developing a non-invasive sampling method to detect early signs of Parkinson’s disease – up to seven years before motor symptoms appear - by analysing the chemical makeup of skin.

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A new study has revealed promising progress in developing a non-invasive sampling method to detect early signs of Parkinson’s disease – up to seven years before motor symptoms appear - by analysing the chemical makeup of skin.

The research, published today in the journal, , demonstrates that compounds or ‘volatiles’ found in sebum — the oily substance produced by our skin —hold key biomarkers for identifying Parkinson’s in its earliest stages.

Using a technique known as Thermal Desorption-Gas Chromatography-Mass Spectrometry (TD-GC-MS), scientists at ֱ, in collaboration with Salford Royal NHS Trust and the Medical University of Innsbruck, analysed skin swabs from participants with Parkinson’s, healthy volunteers, and those with a sleep disorder called isolated REM Sleep Behaviour Disorder (iRBD) — a known early warning sign of Parkinson’s disease.

The results showed that people with iRBD had distinct chemical profiles in their sebum that were different from healthy individuals, but not yet as pronounced as those with established Parkinson’s disease. This supports the idea that Parkinson’s disease leaves a detectable trace on the body well before physical symptoms appear.

Joy-2Joy Milne – the ‘super smeller’ who inspired the research    was also able to distinguish swabs from people with iRBD from the control group and Parkinson’s patients. Intriguingly, she was able to detect both diseases in two of the swabs that came from iRBD individuals, who were later diagnosed with Parkinson’s at their next clinical appointment, after sampling.

Professor Perdita Barran, Professor of Mass Spectrometry at ֱ, said: “This is the first study to demonstrate a molecular diagnostic method for Parkinson’s disease at the prodromal or early stage. It brings us one step closer to a future where a simple, non-invasive skin swab could help identify people at risk before symptoms arise allowing for earlier intervention and improved outcomes.”Joy-13

The study involved more than 80 participants, including 46 people with Parkinson’s, 28 healthy controls, and nine with iRBD.  They found 55 significant features in the sebum that varied between the groups. Those with iRBD often showed levels that sat between the healthy controls and the Parkinson’s group, reinforcing the possibility of detecting the disease in its early phase.

Dr Drupad Trivedi, a researcher from ֱ, built a model that examined the markers in a longitudinal sampling study. He collected samples from Parkinson’s patients over a three-year period and found patterns that suggest this method can also be used to map the progression of the disease, which could have use in refining treatment options and improve patient outcomes.

Joy-7Sebum is also easy to collect using gauze swabs from the face or upper back, making it ideal for non-invasive routine screening and regular monitoring. by the team has also shown it does not need to be stored in the same cold conditions as other biofluids, such as blood, reducing associated costs.

The research is inspired by the observations of Joy Milne, who detected a unique scent in individuals with Parkinson's disease, prompting researchers at ֱ to explore sebum as a source of diagnostic biomarkers.

By using mass spectrometry, a technique that measures the weight of molecules, they have found that there are distinctive Parkinson’s markers in sebum, which has led them to develop this non-invasive swab test.

These findings have recently been validated in another paper, published today in the, where trained dogs were able to detect Parkinson’s in the patients recruited by Prof Barren and Dr Trivedi with remarkable accuracy by smelling skin swabs.

Now, the researchers are continuing to develop and improve the sebum-based testing to eventually use as a practical tool in real-world clinical settings.

Dr Drupad Trivedi, Lecturer in Analytical Measurement Sciences at ֱ, said: "Our goal is to develop a reliable, non-invasive test that helps doctors detect Parkinson’s earlier, track its progression, and ultimately improve patient outcomes.

“We’re also keen to hear from other hyperosmic individuals, potential ‘super smellers’ like Joy, whose remarkable sense of smell could help extend our work to detect other diseases with potential odour signatures."

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This research was published in the journal npj Parkinson's Disease

Full title: Classification of Parkinson’s Disease and idopathic REM Sleep Behaviour Disorder: Delineating Progression Markers from the Sebum Volatilome

DOI: 10.1038/s41531-025-01026-8

Link:

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Biotechnology is enabling us to find new and more sustainable ways to produce chemicals, materials, and everyday products, by understanding and harnessing nature’s own processes and applying them at industrial scales. Supported by the Manchester Institute of Biotechnology, our 400+ experts are innovating solutions in environmental sustainability, health and sustainable manufacturing. Find out more about our biotechnology research.  

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Tue, 15 Jul 2025 09:27:25 +0100 https://content.presspage.com/uploads/1369/0a200456-d57c-4499-b78b-33607fa9413f/500_joy-2.jpg?10000 https://content.presspage.com/uploads/1369/0a200456-d57c-4499-b78b-33607fa9413f/joy-2.jpg?10000
Concretene and GEIC proud to partner for another three years /about/news/concretene-and-geic-proud-to-partner-for-another-three-years/ /about/news/concretene-and-geic-proud-to-partner-for-another-three-years/713567Pioneering construction-tech firm Concretene has chosen the Graphene Engineering Innovation Centre (GEIC) as its base to support manufacturing upscale.  

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We are pleased to announce that pioneering construction-tech firm has chosen the as its base to support manufacturing upscale. The Tier 1 partnership provides laboratory space and extensive access to equipment for quality assurance of raw materials, formulations, and concrete products.

Developed with the support of engineers at ֱ since 2019, Concretene is a graphene-enhanced admixture for concrete that improves compressive strength and durability, enabling removal of cement and a reduced carbon footprint.

The company has extended its production and materials testing facility in the adjacent Pariser Building – part of the new – taking advantage of the advanced materials ecosystem delivered by the GEIC.

Concretene is one of several technologies being developed and applied at the GEIC to explore the potential of graphene in construction. It aims to create a more sustainable and cost-effective solution for the industry by increasing the service life of concrete and reducing cement requirements.

This is an ideal case study for ‘the Manchester model’ of innovation, whereby an idea for the exploitation of nanomaterials is grown through ֱ to become a spin-out company, creating high-value jobs and encouraging inward investment in the city.

Concretene has attracted £1.9m of UK government funding and £6m of venture capital investment since its incorporation in late 2022 and has grown to a staff of 20.

Three Innovate UK-funded projects have delivered significant advances in the application of graphene-enhanced concrete:

  • GraphEnhance – scale-up of graphene and graphene oxide supply chain (with and ).
  • SMART – pre-cast foundation pilings (with )
  • GCRE – low-carbon railway sleepers (with )

Prototype trials have demonstrated compressive strength increases up to 50% in ready-mix applications and 15-20% in pre-cast, all showing compatibility with existing low-carbon concrete mixes incorporating cement replacements (CEM II limestone, CEM III GGBS).

Tests by the Building Research Establishment (BRE) on Concretene’s low-carbon railway sleeper for Cemex have indicated improvements in durability, notably to mitigate shrinkage – a common problem for low-carbon concretes that can lead to cracking and shorter service life.

Collaboration is ongoing with ARUP – the global design and engineering consultancy, which is one of  – and a range of material suppliers to hone specifications for different concrete mixes and applications, with a programme of further scaled trials upcoming to produce the robust dataset required for product certification and launch.

James Baker, CEO of Graphene@Manchester, said:
“We’re incredibly proud to support Concretene’s journey as a standout example of how graphene innovation at the GEIC can scale into real-world industrial impact. Their progress reflects the strength of our collaborative model, which brings together engineers, researchers and industry to tackle global challenges like decarbonising construction. Concretene represents the kind of transformative work we’re driving forward, and we continue to collaborate with a broad range of partners to accelerate the adoption of graphene-enhanced technologies that deliver both environmental and economic benefits.”

Mike Harrison, CEO of Concretene, said:
“We’re really pleased to extend our deal with the GEIC for another three years. Having a dedicated formulation development facility, technical support and high-end microscopy and characterisation kit on site has been invaluable in the development of the product. The proximity of growth and maker space within the Sister Innovation District has allowed us to remain in Manchester and we are grateful of the support from this community.

“We look forward to building on our success to date with the GEIC, commissioning our pilot plant in the Pariser Building and supporting asset owners in their journey to decarbonise concrete in construction.”

 

Advanced materials is one of ֱ’s research beacons - examples of pioneering discoveries, interdisciplinary collaboration and cross-sector partnerships tackling some of the planet's biggest questions. #ResearchBeacons

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Thu, 10 Jul 2025 11:00:00 +0100 https://content.presspage.com/uploads/1369/b784b7af-4c1b-425c-9c7e-7e4653187994/500_concreteneteampic-july2025.jpg?10000 https://content.presspage.com/uploads/1369/b784b7af-4c1b-425c-9c7e-7e4653187994/concreteneteampic-july2025.jpg?10000
ֱ and Brian Cox inspire future scientists in Oldham /about/news/the-university-of-manchester-and-brian-cox-inspire-future-scientists-in-oldham/ /about/news/the-university-of-manchester-and-brian-cox-inspire-future-scientists-in-oldham/713134Renowned physicist and University of Manchester Professor and alumnus Brian Cox, along with Professor Lynne Bianchi (University of Manchester’s Science and Engineering Education Research and Innovation Hub, SEERIH), supported a major initiative aimed at encouraging industry-education links in Oldham.

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The goal was to focus attention on how young people from Oldham can have enhanced opportunities to pursue STEM (Science, Technology, Engineering, and Mathematics)  careers in their town. 

Professor Cox returned to his hometown of Oldham in July for a series of four inspirational ‘Great Horizons’ events. These celebrated STEM education and highlighted the vital role teachers and industry play in shaping future opportunities for young people in Oldham. They were designed to raise the profile of science teachers and science learning, towards igniting ambition in the next generation of scientists, engineers, and innovators.  On Tuesday 1 July, Professor Cox took part in a celebration event for science teachers and leaders from across Oldham’s schools. The event was coordinated by the Cranmer Trust and brought over 250 teachers together to identify how they can take science to a new level in their schools. 

The following day, he engaged with primary school pupils in a ‘tour of the galaxy’ during special morning assemblies, promoting participation in the Great Science Share for Schools. 

In the afternoon, Professor Cox met with business leaders, council representatives, and local influencers, working with Oldham’s Economy Board’s and Oldham Athletic Football club with the remit to lever local business engagement to actively support education and career pathways in STEM. 

Later that evening, he hosted a Q&A session with secondary and college students at Oldham Sixth Form College, sharing insights and answering questions about science and space. 

 ֱ provided leadership in coordinating and hosting the events, with special focus on the primary school event that involved Professor Cox having a whistle-stop tour of 4 primary schools in Oldham, working to ignite the curiosity of hundreds of pupils. Across the town other schools received VIP visits from the Oldham Lord Mayor, industry and charity professionals. These experiences provided opportunity to incentivise schools to become involved in the University’s  flagship campaign, the Great Science Share for Schools, which celebrated its 10th anniversary this year. The campaign encourages young people to ask, investigate and share scientific questions, elevating the prominence of practical science in the classroom. 

Professor Lynne Bianchi, FSE Vice Dean for Social Responsibility, Equality, Diversity and Inclusion, and Director of SEERIH, said: “The two days were powerful in bringing the town’s industry and education partners together. It’s been a real place-based approach that is starting something that will have legacy beyond these launch events. The key now is to harness the energy that spued out of each event and identify key actions that can impact on young people in the short and longer term.’  

Dave Benstead, Chairman of Oldham Enterprise Trust and Oldham’s Economy Board, said: “We set out to optimise STEM-Industry-School-College partnerships which will lead to greater exposure of a variety of STEM career options, broaden student's perspectives and help them make more informed decisions as they progress through education. Our young people need a clearer understanding of the real-world problems that STEM related careers can address and Professor Brian Cox achieved this grabbing their interest and motivation as only he can.” 

With acknowledgments to: Oldham Council, Oldham Enterprise Trust, Oldham Athletic Football Club, Cranmer Education Trust, Pinnacle Learning Trust and SEERIH (ֱ). 

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Mon, 07 Jul 2025 11:35:07 +0100 https://content.presspage.com/uploads/1369/f9bd74dd-0b30-4c22-b23a-399f6ceba3f9/500_briancox.jpg?10000 https://content.presspage.com/uploads/1369/f9bd74dd-0b30-4c22-b23a-399f6ceba3f9/briancox.jpg?10000
Scientists discover giant ‘sinkites’ beneath the North Sea /about/news/scientists-discover-giant-sinkites-beneath-the-north-sea/ /about/news/scientists-discover-giant-sinkites-beneath-the-north-sea/713235Scientists have discovered hundreds of giant sand bodies beneath the North Sea that appear to defy fundamental geological principles and could have important implications for energy and carbon storage.

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Scientists have discovered hundreds of giant sand bodies beneath the North Sea that appear to defy fundamental geological principles and could have important implications for energy and carbon storage.

Using high-resolution 3D seismic (sound wave) imaging, combined with data and rock samples from hundreds of wells, researchers from ֱ in collaboration with industry, identified vast mounds of sand – some several kilometres wide – that appear to have sunk downward, displacing older, lighter and softer materials from beneath them.

The result is stratigraphic inversion - a reversal of the usual geological order in which younger rocks are typically deposited on top of older ones on a previously unseen scale.

While stratigraphic inversion has previously been observed at small scales, the structures discovered by the Manchester team – now named “sinkites” – are the largest example of the phenomenon documented so far.

The finding, in the journal Communications Earth & Environment, challenges scientists understanding of the subsurface and could have implications for carbon storage.

Lead author Professor Mads Huuse from ֱ, said: “This discovery reveals a geological process we haven’t seen before on this scale. What we’ve found are structures where dense sand has sunk into lighter sediments that floated to the top of the sand, effectively flipping the conventional layers we’d expect to see and creating huge mounds beneath the sea.”

It is believed the sinkites formed millions of years ago during the Late Miocene to Pliocene periods, when earthquakes or sudden shifts in underground pressure may have caused the sand to liquefy and sink downward through natural fractures in the seabed. This displaced the underlying, more porous but rigid, ooze rafts - composed largely of microscopic marine fossils - bound by shrinkage cracks, sending them floating upwards. The researchers have dubbed these lighter, uplifted features ‘floatites’.

The finding could help scientists better predict where oil and gas might be trapped and where it’s safe to store carbon dioxide underground.

Prof Huuse said: “This research shows how fluids and sediments can move around in the Earth’s crust in unexpected ways. Understanding how these sinkites formed could significantly change how we assess underground reservoirs, sealing, and fluid migration — all of which are vital for carbon capture and storage”.

Now the team are busy documenting other examples of this process and assessing how exactly it impacts our understanding of subsurface reservoirs and sealing intervals.

Prof Huuse added: “As with many scientific discoveries there are many sceptical voices, but also many who voice their support for the new model. Time and yet more research will tell just how widely applicable the model is.”

This research has been published in the journal Communications Earth & Environment

Full title: Km-scale mounds and sinkites formed by buoyancy driven stratigraphic inversion

DOI:

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Fri, 04 Jul 2025 10:36:00 +0100 https://content.presspage.com/uploads/1369/873126f5-da79-4d08-9491-616956fdbc82/500_northsea.imagefrompixabay.jpg?10000 https://content.presspage.com/uploads/1369/873126f5-da79-4d08-9491-616956fdbc82/northsea.imagefrompixabay.jpg?10000
Celebrating 10 years of the Great Science Share for Schools: 835,135 young people join to explore their scientific questions /about/news/celebrating-10-years-of-the-great-science-share-for-schools-835135-young-people-join-to-explore-their-scientific-questions/ /about/news/celebrating-10-years-of-the-great-science-share-for-schools-835135-young-people-join-to-explore-their-scientific-questions/712885Hundreds of thousands of young people have been asking, investigating and sharing their scientific questions once again this year in the Great Science Share for Schools. 

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Hundreds of thousands of young people have been asking, investigating and sharing their scientific questions once again this year in the Great Science Share for Schools. 

Celebrating its 10th anniversary this year, the campaign inspires teachers of 5-14 year olds to upskill their own knowledge and skills of teaching science enquiry - a form of science education that gives the pupils the opportunity to explore a scientific question through practical investigations linked to .  

Using innovative resources and ideas related to this year’s theme of #ConnectedScience, pupils across the UK and across the world have been taking the lead and becoming science communicators.  The theme illustrates how science is not isolated in learning, but rather, the way we think scientifically has the power to connect our ideas and successes in all areas of our lives. 

The campaign runs throughout the year, leading to registrations from 835,135 pupils sharing on or around Tuesday 17 June. With wider reach across the globe, #GSSfS inspires teachers and educators from 52 different countries to take part, with events taking place across venues such as schools, hospital schools, museums, sports venues and universities.  

This year, ֱ hosted more than 35 schools from across Greater Manchester in its Nancy Rothwell building.  

Some of the questions shared this year included: 

  • Are all flowers the same? 
  • How does wind speed affect voltage generated? 
  • Which type of soil will retain the most water to help keep plants hydrated in hot weather? 
  • How does the temperature of the ocean affect coral? 

The GSSfS campaign was launched by Professor Lynne Bianchi, Vice Dean for Social Responsibility at ֱ, to provide a unique way to elevate the prominence of science in the classroom, focussing on learner-focussed science communication, inclusive and non-competitive engagement, and promoting collaboration.  

Professor Bianchi, said: “It’s been truly inspiring to witness the Great Science Share for Schools reach its 10th anniversary with such global momentum.”

In 2024 and 2025, the campaign was granted the prestigious patronage of the , in recognition of its status as a beacon of excellence in science education and its pivotal role in shaping the next generation of scientists, innovators, and global citizens.  

Now in its 10th year, the GSSfS strategy further develops to explore strategic alliances with ministries of education and schools across the world.  This year the Ministry of Education in Malta and the STEM & VET Curriculum and the Museo de Ciencias Universidad de Navarra in Spain, and the Foundation for Education and Development (FED) Unified Learning Centre in Khao Lak, Thailand have become a key focus for development. 

Grace Marson, Campaign Manager, said: “What Great Science Share for Schools has shown year on year, is that pupils have a thirst for science. They are naturally curious about the world around them and given the opportunity through GSSfS, they demonstrate that they can ask amazing scientific questions. This campaign puts pupils at the centre of their learning.”  

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Wed, 02 Jul 2025 12:13:01 +0100 https://content.presspage.com/uploads/1369/b0353805-4da0-4397-b00d-2cbf507345a1/500_stmargaretmarysrcprimaryschoolmanchester.jpg?10000 https://content.presspage.com/uploads/1369/b0353805-4da0-4397-b00d-2cbf507345a1/stmargaretmarysrcprimaryschoolmanchester.jpg?10000
New project to pioneer the principles of human genome synthesis /about/news/new-project-to-pioneer-the-principles-of-human-genome-synthesis/ /about/news/new-project-to-pioneer-the-principles-of-human-genome-synthesis/712464An ambitious new research project, SynHG (Synthetic Human Genome), is aiming to develop the foundational and scalable tools, technology and methods needed to synthesise human genomes. Through programmable synthesis of genetic material we will unlock a deeper understanding of life, leading to profound impacts on biotechnology, potentially accelerating the development of safe, targeted, cell-based therapies, and opening entire new fields of research in human health. Achieving reliable genome design and synthesis – i.e. engineering cells to have specific functions – will be a major milestone in modern biology

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An ambitious new research project, SynHG (Synthetic Human Genome), is aiming to develop the foundational and scalable tools, technology and methods needed to synthesise human genomes. Through programmable synthesis of genetic material we will unlock a deeper understanding of life, leading to profound impacts on biotechnology, potentially accelerating the development of safe, targeted, cell-based therapies, and opening entire new fields of research in human health. Achieving reliable genome design and synthesis – i.e. engineering cells to have specific functions – will be a major milestone in modern biology. 

The five-year multi-centre research project – supported by £10mn funding from Wellcome – involves researchers from the Universities of Cambridge, Kent, Manchester, Oxford, and Imperial College London. SynHG is led by Professor Jason Chin of the MRC Laboratory of Molecular Biology; he was also recently announced as the founding Director of the Generative Biology Institute at the Ellison Institute of Technology, Oxford, and a Professor at the University of Oxford.

A dedicated social science programme, led by Professor Joy Zhang of the Centre for Global Science and Epistemic Justice at the University of Kent, runs throughout the project alongside the scientific development. The programme will work with civil society partners around the world to actively explore, assess and respond to the socio-ethical implications of tools and technologies developed by SynHG.

The benefits of human genome synthesis to research and beyond 
Since the completion of the Human Genome Project at the start of the century, researchers have sought the ability to write our genome from scratch. Unlike genome editing, genome synthesis allows for changes at a greater scale and density, with more accuracy and efficiency, and will lead to the determination of causal relationships between the organisation of the human genome and how our body functions. Synthetic genomes have the potential to open up brand new areas of research in creating targeted cell-based therapies, virus-resistant tissue transplantation and extensions may even enable the engineering of plant species with new properties, including the ability to withstand harsh climate. 

To date, scientists have successfully developed synthetic genomes for microbes such as E. coli. The field of synthetic genomics has accelerated in recent times, and advances in machine learning, data science and AI showing promise, with synthesised DNA becoming more widely available. However, today’s technology is not able to produce large, more complex sections of genetic material, such as found in crops, animals and humans. 

The research team are focusing on developing the tools and technology to synthesise large genomes exemplified by the human genome. Focusing on the human genome, as opposed to other model organisms such as mice, will allow researchers to more quickly make transformative discoveries in human biology and health.

 Professor Jason Chin, Founding Director of the Generative Biology Institute at EIT, Oxford, said: “The ability to synthesize large genomes, including genomes for human cells, may transform our understanding of genome biology and profoundly alter the horizons of biotechnology and medicine. With SynHG we are building the tools to make large genome synthesis a reality, and at the same time we are pro-actively engaging in the social, ethical, economic and policy questions that may arise as the tools and technologies advance.  We hope that Wellcome’s support for this combination of approaches will help facilitate substantive societal benefit.”

A bold, ambitious project facing complex scientific challenges 
SynHG focuses on developing the foundational tools and methods required to equip more researchers in the future. This research journey will potentially catalyse new technologies in the field of engineering biology, generating exciting discoveries about how cells use their genomes even before achieving complete genome synthesis. 

The team of researchers hope to provide proof of concept for large genome synthesis by creating a fully synthetic human chromosome, which makes up approximately 2% of our total DNA. Initially, the team hope to establish methods where small changes are made to the sequence of a chromosome with minimal onward effect on the proteins that it produces. 

Setting the foundation – testing the concept, iterating the methods, and embedding ethical considerations – could alone take many years. Even as engineering biology technologies improve, reliably building a complete synthetic human genome and meaningfully applying it to human health will likely take decades.

Michael Dunn, Director of Discovery Research at Wellcome, said: “Our DNA determines who we are and how our bodies work and with recent technological advances, the SynHG project is at the forefront of one of the most exciting areas of scientific research. Through creating the necessary tools and methods to synthesise a human genome we will answer questions about our health and disease that we cannot even anticipate yet, in turn transforming our understanding of life and wellbeing.” 

Professor Patrick Yizhi Cai, Chair of Synthetic Genomics at the University of Manchester said: "We are leveraging cutting-edge generative AI and advanced robotic assembly technologies to revolutionize synthetic mammalian chromosome engineering. Our innovative approach aims to develop transformative solutions for the pressing societal challenges of our time, creating a more sustainable and healthier future for all."

Embedding global socio-ethical discussions in scientific advancements 
To effectively translate scientific ambition into meaningful and potentially profound societal benefits, it is essential that there is proactive and sustained engagement with the evolving socio-ethical priorities and concerns of diverse communities. 

Wellcome is also funding Care-full Synthesis, a dedicated social research initiative conducting empirical studies with diverse publics worldwide. Led by Professor Joy Y. Zhang and hosted by the Centre for Global Science and Epistemic Justice (GSEJ) at the University of Kent, the project builds on GSEJ’s global network of academic, civil society, industry and policy partners to promote a new approach of science–society dialogue that is Open, Deliberative, Enabling, Sensible & Sensitive, and Innovative (‘ODESSI’). 

Professor Joy Zhang, Founding Director of the GSEJ at the University of Kent said: “With Care-full Synthesis, through empirical studies across Europe, Asia-Pacific, Africa, and the Americas, we aim to establish a new paradigm for accountable scientific and innovative practices in the global age—one that explores the full potential of synthesising technical possibilities and diverse socio-ethical perspectives with care.” 

Over the next five years, the team will undertake a transdisciplinary and transcultural investigation into the socio-ethical, economic, and policy implications of synthesising human genomes. The project places particular emphasis on fostering inclusivity within and across nation-states, while engaging emerging public–private partnerships and new interest groups. 

Through the generation of rich empirical data, the team will develop a toolkit to enable effective integration of careful thinking into the management, communication, and delivery of human genome synthesis. This work aims to substantially expand the practice of accountable science and innovation, reflecting the complex realities of a hyperconnected yet ideologically fragmented world. Care-full Synthesis will achieve this by advancing a fresh approach to engaging with global communities, ensuring that fast-moving science is accompanied by robust social and legal deliberation, and identifying innovative strategies to co-ordinate regional and global governance accounting for diverse social priorities and scientific pathways.

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Fri, 27 Jun 2025 08:49:39 +0100 https://content.presspage.com/uploads/1369/ce302eb8-856a-4c73-973b-e23549abe6d8/500_febstock-photo-dna-helix-gene-molecule-spiral-loop-d-genetic-chromosome-cell-dna-molecule-spiral-of-blue-light-1559659808.jpg?10000 https://content.presspage.com/uploads/1369/ce302eb8-856a-4c73-973b-e23549abe6d8/febstock-photo-dna-helix-gene-molecule-spiral-loop-d-genetic-chromosome-cell-dna-molecule-spiral-of-blue-light-1559659808.jpg?10000
Four researchers promoted in the Manchester Institute of Biotechnology /about/news/four-researchers-promoted-in-the-manchester-institute-of-biotechnology/ /about/news/four-researchers-promoted-in-the-manchester-institute-of-biotechnology/712368We are delighted to announce the promotions of four outstanding members of our academic staff. These well-deserved recognitions mark not only individual achievement but also the collective success of their research groups, collaborators, and the wider academic community.

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, and home to the , we are focused on finding new and more sustainable ways to produce chemicals, materials, and everyday products, by understanding and harnessing nature’s own processes and applying them at industrial scales. Find out more via our .

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Neil Dixon – promoted to Professor of Sustainable Biotechnology

Neil’s pioneering research focuses on engineering microbial systems for sustainable applications such as bioremediation, biosensing, and transforming carbon-rich waste into valuable bioproducts. His team has developed novel biotechnological processes using engineered microbes and consortia to convert mixed waste streams into high-value biopolymers and chemical building blocks, contributing significantly to circular economy initiatives.

Neil leads the UK contingent of the international CIRCLE project, which aims to repurpose carbon-rich waste as a feedstock for the chemical industry. He also played a key role in fostering international collaboration as the founding programme director of a dual PhD in Synthetic and Systems Biology with Tsinghua University.

Reflecting on his promotion, Neil said:

Sophie Nixon – promoted to Professor of Environmental Microbiology and Biotechnology

Sophie leads research at the interface of environmental microbiology and biotechnology, exploring how microbial communities cycle carbon in extreme natural and engineered environments. Her work bridges fundamental discovery and applied innovation, with a focus on harnessing microbial processes for sustainable biotechnologies. She leads a £5.4 million BBSRC-funded programme investigating the rules of life in hot spring microbiomes to support the development of efficient CO-upcycling strategies for heavy industry. Sophie is also internationally recognised for her research into microbial life in deep subsurface environments relevant to geological CO storage.

A recipient of the 2023 L’Oréal-UNESCO For Women in Science Rising Talent award for Sustainable Development, she collaborates with global industry partners including Equinor, ExxonMobil, bp, and Unilever.

Commenting on her promotion, Sophie said:

James Winterburn – promoted to Professor of Biochemical Engineering

We also congratulate James Winterburn, who has been promoted to Professor of Biochemical Engineering. As an affiliate member of the MIB, James  works closely with MIB researchers and focuses on using industrial biotechnology to develop sustainable, bio-based alternatives to petrochemicals. His work spans biomass pretreatment, fermentation process design, downstream processing, and bioproduct applications.

James is a Co-Founder of Holiferm Limited, which was spun out of his research group in 2018. Holiferm has since commercialised patented biosurfactant technologies and now manufactures sophorolipid biosurfactants at kilotonne scale.

Commenting on the promotion, James said:

Lu Shin Wong – promoted to Reader

Congratulations also to Lu Shin Wong, who has been promoted to Reader. Lu Shin’s research explores the mechanisms of enzymatic reactions and their applications in sustainable chemical synthesis. His work includes the study of enzymes that cleave and condense silicon-oxygen bonds—research that has shed light on the enzymes’ evolutionary origins and potential in silicon chemistry. He also works on enzymes that catalyse oxidation reactions, with applications in recycling and detoxification.

Lu Shin leads Manchester’s component of the £13M UKRI Preventing Plastic Pollution with Engineering Biology (P3EB) Mission Hub. He is an external reviewer for the Karlsruhe Nano Micro Facility, the Belgian funding agency FWO, and the UKRI fellowships college; and received a Highly Commended “Lecturer of the Year” Award at the FSE Students’ Awards in 2021.

Speaking about his promotion, Lu Shin said:

Professor Anthony Green, Director of the Manchester Institute of Biotechnology said of the promotions:

Please join us in congratulating Neil, Sophie, James, and Lu Shin on their achievements. Their contributions continue to shape the future of sustainable biotechnology and engineering biology.

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Thu, 26 Jun 2025 13:53:10 +0100 https://content.presspage.com/uploads/1369/a181056c-8bed-4dd0-a6f4-d6467f43cade/500_250626promotions-banner.jpg?10000 https://content.presspage.com/uploads/1369/a181056c-8bed-4dd0-a6f4-d6467f43cade/250626promotions-banner.jpg?10000
Manchester chemists create molecular magnet that could boost data storage by 100 times /about/news/manchester-chemists-create-molecular-magnet-that-could-boost-data-storage-by-100-times/ /about/news/manchester-chemists-create-molecular-magnet-that-could-boost-data-storage-by-100-times/712072Scientists at ֱ have designed a molecule that can remember magnetic information at the highest temperature ever recorded for this kind of material.

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Scientists at ֱ have designed a molecule that can remember magnetic information at the highest temperature ever recorded for this kind of material.

In a boon for the future of data storage technologies, the researchers have made a new single-molecule magnet that retains its magnetic memory up to 100 Kelvin (-173 °C) – around the temperature of the Moon at night.

The finding, published in the journal , is a significant advance on the previous record of 80 Kelvin (-193 °C). While still a long way from working in a standard freezer, or at room temperature, data storage at 100 Kelvin could be feasible in huge data centres, such as those used by Google.

If perfected, these single-molecule magnets could pack vast amounts of information into incredibly small spaces – possibly more than three terabytes of data per square centimetre. That’s around half a million TikTok videos squeezed into a hard drive that’s the size of a postage stamp.

The research was led by ֱ, with computational modelling led by the Australian National University (ANU).

David Mills, Professor of Inorganic Chemistry at ֱ, said: “This research showcases the power of chemists to deliberately design and build molecules with targeted properties. The results are an exciting prospect for the use of single-molecule magnets in data storage media that is 100 times more dense than the absolute limit of current technologies.

“Although the new magnet still needs cooling far below room temperature, it is now well above the temperature of liquid nitrogen (77 Kelvin), which is a readily available coolant. So, while we won’t be seeing this type of data storage in our mobile phones for a while, it does make storing information in huge data centres more feasible.”

Magnetic materials have long played an important role in data storage technologies. Currently, hard drives store data by magnetising tiny regions made up of many atoms all working together to retain memory. Single-molecule magnets can store information individually and don’t need help from any neighbouring atoms to retain their memory, offering the potential for incredibly high data density. But, until now, the challenge has always been the incredibly cold temperatures needed in order for them to function.

The key to the new magnets’ success is its unique structure, with the element dysprosium located between two nitrogen atoms. These three atoms are arranged almost in a straight line – a configuration predicted to boost magnetic performance but realised now for the first time.

Usually, when dysprosium is bonded to only two nitrogen atoms it tends to form molecules with more bent or irregular shapes. In the new molecule, the researchers added a chemical group called an alkene that acts like a molecular pin, binding to dysprosium to hold the structure in place.

The team at the Australian National University developed a new theoretical model to simulate the molecule’s magnetic behaviour to allow them to explain why this particular molecular magnet performs so well compared to previous designs.

Now, the researchers will use these results as a blueprint to guide the design of even better molecular magnets.

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Wed, 25 Jun 2025 16:00:00 +0100 https://content.presspage.com/uploads/1369/4f4797fd-4542-472a-889d-44da47d40996/500_rsc-chilton-20250620-anu4052.jpg?10000 https://content.presspage.com/uploads/1369/4f4797fd-4542-472a-889d-44da47d40996/rsc-chilton-20250620-anu4052.jpg?10000
Goodbye to a founder of radio astronomy /about/news/goodbye-to-a-founder-of-radio-astronomy/ /about/news/goodbye-to-a-founder-of-radio-astronomy/712176We are sad to report that one of the founders of the science of radio astronomy, Sir Francis Graham-Smith FRS, FRAS, FInstP, has passed away at the age of 102.

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We are sad to report that one of the founders of the science of radio astronomy, Sir Francis Graham-Smith FRS, FRAS, FInstP, has passed away at the age of 102.

Sir Francis, or Graham as he was known to friends and colleagues, was the second Director of Jodrell Bank Observatory, taking over from Sir Bernard Lovell when he retired in 1981.

His career in astronomy was remarkable.

During the Second World War, Graham had been forced to interrupt his university studies in Cambridge in order to work on the development of radar. At the end of the war, he returned to Cambridge and began working alongside Martin Ryle, another wartime radar expert. There he played a key role in pioneering the new science of radio astronomy, providing some of the most accurate positions for the newly discovered sources of cosmic radio waves using interferometers.  

In 1964, he was appointed as a Professor of Radio Astronomy at ֱ and moved to Jodrell Bank. He worked on some early space-based radio astronomy experiments as well as ground-based detection of cosmic rays.

However, when pulsars were discovered by Jocelyn Bell and Antony Hewish at Cambridge in 1967, his focus switched immediately to these new and important phenomena. Their study, using the Lovell Telescope at Jodrell Bank and others, was to occupy much of the remainder of his career.

Whilst Director of Jodrell Bank, Graham was instrumental in securing funding for a significant upgrade to the MERLIN telescopes, Jodrell Bank’s own interferometer network, including the addition of a new 32-metre telescope to be sited in Cambridge. This upgrade kept MERLIN at the leading edge throughout the 1990s and paved the way for the later development to e-MERLIN and the Observatory today.

Although he officially retired in 1988, Graham continued to be an active member of Jodrell Bank’s pulsar research group, completing the latest edition of the research text ‘Pulsar Astronomy’ in his 99th year and publishing a review of Fast Radio Bursts in only April of this year, at the age of 102.

In 1970, Graham was elected as a Fellow of the Royal Society. He then became Director of the Royal Greenwich Observatory in 1975 where he oversaw the development of the UK’s optical observatory on La Palma in the Canary Islands. In 1981, he returned to Jodrell Bank to take over as Director when Sir Bernard Lovell retired. From 1975 to 1977, he was President of the Royal Astronomical Society and, from 1982 to 1990, he was Astronomer Royal. He received a knighthood in 1986.

Outside his work in research and scientific management, Graham was always a strong supporter of and participant in public engagement with science and education. For example, he delivered the 1965 Royal Institution Christmas Lecture alongside fellow radio astronomers Sir Bernard Lovell, Sir Martin Ryle and Antony Hewish. Amongst many other activities, including writing popular books and research-level texts, he played a significant role in the development and management of the public visitor centre at Jodrell Bank.

Graham was married to Elizabeth, his wife of 76 years who died in 2021.  They had four children.  He was a keen gardener and, for many years, an avid bee-keeper, an interest which he retained well into his 90s.

Selected recent books

  • Pulsar Astronomy
    Lyne, A. G., Graham-Smith, F., Stappers, B. (CUP, 2022). .
  •  An Introduction to Radio Astronomy
    Burke, B. F., Graham-Smith, F., Wilkinson, P. N. (CUP, 2019). .
  • Eyes on the Sky: A Spectrum of Telescopes
    Graham-Smith, F. (OUP, 2016). .
  • Unseen Cosmos: The Universe in Radio
    Graham-Smith, F. (OUP, 2013). .

Selected research papers

  • A New Intense Source of Radio-Frequency Radiation in the Constellation of Cassiopeia
    Ryle, M., Smith, F. G., Nature (1949). .
  • An Accurate Determination of the Positions of Four Radio Stars
    Smith, F. G., Nature (1951). .
  • Radio Pulses from Extensive Cosmic-Ray Air Showers
    Jelley, J. V. et al (1965). .
  • Characteristics of the radio pulses from the pulsars
    Lyne, A. G., Smith, F. G., Graham, D. A., MNRAS (1971). .
  • Crab pulsar timing 1982-87
    Lyne, A. G., Pritchard, R. S., Smith, F. G., MNRAS (1988). .
  • Statistical studies of pulsar glitches
    Lyne, A. G., Shemar, S. L., Smith, F. Graham, MNRAS (2000). .
  • Pulsars: a concise introduction 
    Graham-Smith, F. , Lyne, A. G., A&G (2023). .
  • A new era for FRBs
    Graham-Smith, Francis, A&G (2025). .

Recent interviews

  • (BBC Science Café from 2023)
  • (Jodcast from 2016).
  • (Jodcast from 2015).

 

Obituary written by Professor Tim O'Brien.

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Wed, 25 Jun 2025 13:04:39 +0100 https://content.presspage.com/uploads/1369/d15b2061-ebc9-4c4a-bbf8-9272234aec99/500_sirfrancisgraham-smith-2014.png?10000 https://content.presspage.com/uploads/1369/d15b2061-ebc9-4c4a-bbf8-9272234aec99/sirfrancisgraham-smith-2014.png?10000
Four University colleagues win prestigious Royal Society of Chemistry prizes /about/news/four-university-colleagues-win-prestigious-royal-society-of-chemistry-prizes/ /about/news/four-university-colleagues-win-prestigious-royal-society-of-chemistry-prizes/712054Four University of Manchester colleagues have been honoured by the Royal Society of Chemistry for their outstanding contributions to the chemical sciences.

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Four University of Manchester colleagues have been honoured by the Royal Society of Chemistry for their outstanding contributions to the chemical sciences.

has been selected to receive the Robert Robinson Prize, while is one of this year's three Tilden Prize recipients.

Professor Larrosa and Professor Barran are among the more than 40 Research and Innovation Prize winners, which recognises researchers who have displayed their brilliance when it comes to research and innovation.

and have earned the Technical Excellence Prize for their outstanding dedication and technical expertise in running the at ֱ. The prize recognises outstanding contributions to the chemical sciences made by individuals or teams working as technicians or in technical roles. 

Prof Larrosa won his prize for contributions to organic chemistry in the area of ruthenium-catalysed C–C bond formation, and receives £3,000 and a medal.

His investigates the development of catalytic processes that enable chemists in industry and academia to synthesise valuable molecules in a more straightforward and sustainable fashion. The main approach in the group involves the application of analytical tools to the detailed study of the modes of operation of transition metal catalysts, and then using this new knowledge to develop more powerful and efficient catalysts.

After receiving the prize, Prof Larrosa said: “It is such an honour to receive the Robert Robinson Award, especially given its history of celebrating transformative contributions to organic chemistry. This recognition reflects the creativity, persistence and collaborative spirit of the brilliant researchers I have had the privilege to work with over the years. I am proud of what we have achieved together, and deeply grateful for the support of my colleagues, mentors and the wider scientific community.”

Professor Barran was recognised with the Tilden Prize for her work on the application of ion mobility mass spectrometry to complex biological systems, and breakthroughs in biomarker discovery – notably non-invasive sampling to diagnose Parkinson's disease.

Her focuses on developing advanced mass spectrometry techniques to study the structure and behaviour of proteins and other biomolecules, with applications in understanding the fundamentals of biology, the mechanistic reasons for diseases and the development of therapeutics and diagnostics. One of our most notable achievements is the collaborative work with Joy Milne, a retired nurse who possesses an extraordinary sense of smell and noticed a distinct odour associated with Parkinson’s disease.

This observation led to research demonstrating that sebum, an oily substance secreted by the skin, contains compounds that can serve as biomarkers for Parkinson’s. Using mass spectrometry, our team identified specific molecules in sebum that differ between individuals with and without Parkinson’s disease. This discovery has paved the way for the development of a non-invasively sampled and rapid diagnostic test that can detect Parkinson’s disease with high accuracy, potentially allowing for earlier intervention and treatment.

Prof Barran won £5,000 and a medal. 

After receiving the prize, Prof Barran said: “I was absolutely thrilled! This prize was formally won by both my PhD advisors, Harry Kroto and Tony Stace, my undergraduate personal tutor, Dave Garner, and many other brilliant scientists. I felt totally honoured to be among these people who I have always respected. In my case, I attribute winning to the people that I have been privileged to work with. I noted that out of about 200 recipients I was the ninth female. This also made me feel pretty pleased!”

Dr Muralidharan Shanmugam and Adam Brookfield are two EPSRC National Research Facility (NRF) for Electron Paramagnetic Resonance Spectroscopy technical specialists named as the winners of one of the Royal Society of Chemistry’s team prizes, which celebrate discoveries and innovations that push the boundaries of science.

The duo have been recognised for their outstanding dedication and technical expertise in running the facility at ֱ. Electron paramagnetic resonance (EPR) is the spectroscopic technique that is selective and sensitive to unpaired electrons. The unpaired electrons could be intrinsic to the materials studied or could be induced via a process (e.g light/heat/chemically) to provide information on structure, kinetics and much more, with applications covering all areas of physics, chemistry, biology and materials science. The technical team at the EPSRC NRF both maintain the equipment and assist users with the design, implementation and analysis of proposed experiments.

They will share £3,000 and receive a trophy.

 After receiving the prize, Adam Brookfield said: “Both Murali and I are over the moon that our contributions have been recognised by the RSC with this award.

"We're both nosey scientists at heart, we want to provide the best instrument access and knowledge to our users to enable their world-class science. We're in a unique position where we get to see and adapt the facility to the trends and hotspots in research areas, alongside training the next generation of scientific leaders.”

The Royal Society of Chemistry’s prizes have recognised excellence in the chemical sciences for more than 150 years. This year’s winners join a prestigious list of past recipients in the RSC’s prize portfolio, 60 of whom have gone on to win Nobel Prizes for their work, including 2022 Nobel laureate Carolyn Bertozzi and 2019 Nobel laureate John B Goodenough.

Dr Helen Pain, Chief Executive of the Royal Society of Chemistry, said: “The chemical sciences cover a rich and diverse collection of disciplines, from fundamental understanding of materials and the living world, to applications in medicine, sustainability, technology and more. By working together across borders and disciplines, chemists are finding solutions to some of the world’s most pressing challenges.

“Our prize winners come from a vast array of backgrounds, all contributing in different ways to our knowledge base, and bringing fresh ideas and innovations. We recognise chemical scientists from every career stage and every role type, including those who contribute to the RSC’s work as volunteers. We celebrate winners from both industry and academia, as well as individuals, teams, and the science itself.

“Their passion, dedication and brilliance are an inspiration. I extend my warmest congratulations to them all.”

For more information about the RSC’s prizes portfolio, visit .

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Wed, 25 Jun 2025 11:00:00 +0100 https://content.presspage.com/uploads/1369/6cb9e2c0-8a68-40ed-8cb8-2ee4b2293b16/500_untitleddesign8.png?10000 https://content.presspage.com/uploads/1369/6cb9e2c0-8a68-40ed-8cb8-2ee4b2293b16/untitleddesign8.png?10000
Manchester astronomers reveal first look from the world’s largest digital camera /about/news/manchester-astronomers-reveal-first-look-from-the-worlds-largest-digital-camera/ /about/news/manchester-astronomers-reveal-first-look-from-the-worlds-largest-digital-camera/712070Astronomers have revealed the first images from “the most ambitious astronomical survey to date” – a mission that will transform our understanding of the Universe.

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Astronomers have revealed the first images from “the most ambitious astronomical survey to date” – a mission that will transform our understanding of the Universe.

The Vera C. Rubin Observatory in Chile, has released a series of extraordinary images, which show millions of galaxies, stars in the Milky Way and thousands of asteroids, all in unprecedented detail.  

These images, captured in just 10 hours of observations, offer a glimpse of what’s to come from Rubin’s forthcoming Legacy Survey of Space and Time (LSST) - a 10-year mission to build the most detailed time-lapse map of the night sky ever attempted.

The UK is playing a major role in the global collaboration, as the second-largest international contributor to the project, supported by a £23 million investment from the Science and Technology Facilities Council (STFC).

The UK will host one of three international data facilities to support management and processing of the unprecedented amounts of data that Rubin will produce.

Among the UK scientists closely involved is Professor Chris Conselice, Professor of Extragalactic Astronomy at ֱ. Professor Conselice sits on the UK:LSST/Rubin Board and has contributed to key scientific analyses for preparation of the data, including techniques to detect very diffuse light around galaxies and how the data from Rubin can be used with Euclid - another international satellite mission to map the dark universe.

The images have been taken with the LSST Camera - the world’s newest and most powerful survey telescope, equipped with the largest digital camera ever built and feeds a powerful data processing system.

Over the next decade, it will repeatedly scan the sky to create an ultra-wide, ultra-high-definition time-lapse record of our Universe that will bring the sky to life with a treasure trove of billions of scientific discoveries. The images will reveal asteroids and comets, pulsating stars, supernova explosions, far-off galaxies and perhaps cosmic phenomena that no one has seen before.

Already, the camera has identified more than 2000 never-before-seen asteroids in our Solar System.

The project will generate the largest dataset in the history of optical astronomy. The amount of data gathered by Rubin Observatory in its first year alone will be greater than that collected by all other optical observatories combined.

The dataset is expected to reach around 500 petabytes and catalogue billions of cosmic objects with trillions of measurements that will help scientists make countless discoveries about the Universe and will serve as an incomparable resource for scientific exploration for decades to come.

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Tue, 24 Jun 2025 15:43:24 +0100 https://content.presspage.com/uploads/1369/48d5a700-75a5-432b-bea7-81753f6fcbf5/500_lm4-trifid-10k.jpg?10000 https://content.presspage.com/uploads/1369/48d5a700-75a5-432b-bea7-81753f6fcbf5/lm4-trifid-10k.jpg?10000
ֱ joins global leaders to strengthen UK-Korea collaboration in engineering biology /about/news/uom-uk-korea-collaboration-in-engineering-biology/ /about/news/uom-uk-korea-collaboration-in-engineering-biology/711702, and and from the (MIB) joined global leaders in engineering biology at the UK-Korea Engineering Biology Symposium held on 12 June at Imperial College London’s White City Innovation District to help shape the future of international collaboration in the space.

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, and home to the , we are focused on finding new and more sustainable ways to produce chemicals, materials, and everyday products, by understanding and harnessing nature’s own processes and applying them at industrial scales. Find out more via our .

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The symposium marked a major milestone in the growing strategic partnership between the UK and South Korea, bringing together researchers, innovators, government representatives, and funders to explore collaborative opportunities in one of the most promising nascent scientific fields.

Driving innovation through global partnerships

At the symposium, a key highlight was the signing of a Memorandum of Understanding (MoU) between ֱ, the Korea Advanced Institute of Science and Technology (KAIST), and the Korea Research Institute of Bioscience and Biotechnology (KRIBB). The agreement formalises a new phase of collaboration, focused on:

  • Joint research and innovation in engineering biology
  • Shared access to biofoundry infrastructure and protocol
  • Researcher exchange programmes and skills development

Professor Neil Dixon, Professor of Sustainable Biotechnology at the Manchester Institute of Biotechnology, signed the MoU on behalf of the Institution. Commenting on the MoU, he noted:

This international partnership is backed by the UK Department for Science, Innovation and Technology (DSIT), the British Embassy in Seoul, and Korean national funders. An additional £250,000 in UK government funding, recently announced, will support the expansion of collaborative programmes, including joint workflow development and extended researcher exchanges.

Looking ahead

Engineering Biology— an area that applies engineering principles to biological systems to help society design and manufacture key chemicals more sustainably —holds immense promise across health, agriculture, energy, and sustainability. ֱ, currently , is home to the internationally-recognised Manchester Institute of Biotechnology which works at the cutting-edge of engineering biology discovering, and designing new ways to manufacture key chemicals for industries as wide ranging as pharmaceuticals, to agrochemicals, to food and biofuels. The MIB has long supported and developed its international collaborations and is cementing its relationship with South Korea through this new initiative.

As part of this UK-Korea partnership, ֱ will continue to play a leading role in the translation of engineering biology into technologies that address major global challenges—from clean energy to sustainable agriculture to advanced therapeutics.

International collaborations such as the UK – South Korea International Research Partnership for Engineering Biology help to unite science, policy, and industry in pursuit of real-world solutions. For Manchester, this marks a bold step forward in delivering on its mission of global impact through science and innovation.

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Fri, 20 Jun 2025 12:19:20 +0100 https://content.presspage.com/uploads/1369/c5b67238-10aa-4279-a3d7-d9f035192912/500_mousigning-neildixon-sangyuplee2.jpg?10000 https://content.presspage.com/uploads/1369/c5b67238-10aa-4279-a3d7-d9f035192912/mousigning-neildixon-sangyuplee2.jpg?10000
University research leads to Scotland’s largest maritime decarbonisation project /about/news/university-research-leads-to-scotlands-largest-maritime-decarbonisation-project/ /about/news/university-research-leads-to-scotlands-largest-maritime-decarbonisation-project/711645A significant new milestone in green energy has been achieved in Scotland, underpinned by research from the Tyndall Centre for Climate Change Research at ֱ.

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A significant new milestone in green energy has been achieved in Scotland, underpinned by research from the Tyndall Centre for Climate Change Research at ֱ.

Port of Aberdeen has officially launched its new shore power system—Scotland’s largest maritime decarbonisation initiative to date—which allows ships to switch off their fossil fuel engines while docked and connect instead to clean, low-carbon shore power. This transition significantly reduces greenhouse gas emissions, improves air quality, and lowers noise levels in Aberdeen’s busy harbour.

Now live across five berths in North Harbour—with additional capacity to expand—the installation is expected to reduce up to 60,000 tonnes of CO₂ equivalent over the next 20 years. This saving is equivalent to removing approximately 2,140 cars from the road each year. also sets out how UK Government policy changes could support faster deployment of shore power at other ports.

The success of the project not only helps Aberdeen advance its ambition to become the UK’s first net zero port by 2040 but also demonstrates the crucial role university research plays in real-world climate solutions. Dr Bullock and the Tyndall team’s sustained involvement from early research to full deployment highlights the lasting value of academic contributions to national decarbonisation efforts.

The project, known as Shore Power in Operation, is part of the UK Department for Transport’s Zero Emission Vessels and Infrastructure (ZEVI) competition, delivered through UK SHORE and Innovate UK. With £4 million in funding and extensive collaboration between industry and academia, it represents a landmark public-private investment in cleaner port infrastructure.

Port of Aberdeen led the initiative in partnership with a broad consortium including OSM Offshore, Tidewater Marine UK Ltd, Connected Places Catapult, and researchers from the Tyndall Centre based in the University of Manchester, with support from Buro Happold and Energy Systems Catapult. PowerCon, a global leader in shore power solutions, delivered the on-site infrastructure.

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Thu, 19 Jun 2025 15:38:33 +0100 https://content.presspage.com/uploads/1369/bc21f2c5-9e05-498c-b37b-debf19ef60b8/500_20250612-poa-shore-power-050.jpg?10000 https://content.presspage.com/uploads/1369/bc21f2c5-9e05-498c-b37b-debf19ef60b8/20250612-poa-shore-power-050.jpg?10000
ֱ joins two new national research hubs to drive sustainable manufacturing /about/news/two-new-national-research-hubs-to-drive-sustainable-manufacturing/ /about/news/two-new-national-research-hubs-to-drive-sustainable-manufacturing/711596Backed by a combined investment of nearly £28 million from the Engineering and Physical Sciences Research Council (EPSRC) and the Department for Science, Innovation and Technology (DSIT), ֱ partners with the University of Edinburgh and the University of Warwick in two new UK-wide research hubs that will reshape the future of sustainable manufacturing.

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Advanced materials

We’re home to 700 materials experts, revolutionising industries by developing advanced materials that unlock new levels of performance, efficiency, and sustainability. Supported by the £885m campus investment over the last 10 years, our researchers are at the forefront of materials innovation, creating game-changing solutions. From healthcare to manufacturing, we’re tackling global challenges and ensuring the UK's reputation as a technology ‘super power'. Find out more about our advanced materials research.

Biotechnology

, and home to the , we are focused on finding new and more sustainable ways to produce chemicals, materials, and everyday products, by understanding and harnessing nature’s own processes and applying them at industrial scales. Find out more via our .

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As the UK accelerates toward net-zero and a circular economy, the Sustainable Engineering Plastics (SEP) and Carbon-Loop Sustainable Biomanufacturing (C-Loop) hubs bring together world-leading academic and industry partners to tackle major sustainability challenges through innovation in engineering plastics and biomanufacturing.

A circular future for engineering plastics 

Manchester researchers will work alongside the University of Warwick and University College London as part of the new EPSRC Manufacturing Research Hub in Sustainable Engineering Plastics (SEP). The £13.6 million initiative will assess and improve the sustainability of greener materials and remanufacturing processes through reusing, repairing, and recycling high performance and durable plastics used in vehicles, electronics, and construction.

The Manchester team will be led by Professor Michael Shaver through the Sustainable Materials Innovation Hub and Sustainable Futures platform. The EPSRC SEP Hub will engage over 60 industry partners across supply chains including Siemens, Polestar, Biffa and Vita to accelerate the real-world adoption of sustainable plastic solutions.

Microbes turning waste into wealth 

In parallel, Manchester will join to the Carbon-Loop Sustainable Biomanufacturing Hub (C-Loop), a £14 million initiative led by the University of Edinburgh, alongside other spokes at Nottingham, University College London and Imperial College London, with more than 40 industry collaborator partnerships. Drawing on expertise at the Manchester Institute of Biotechnology (MIB), researchers will explore how engineered microbial systems can convert carbon-rich industrial waste into high-value products such as cosmetics, material precursors and solvents.

Professor Neil Dixon will lead the Manchester team, leveraging MIB’s global leadership in engineering biology platforms and sustainable biomanufacturing. As part of the C-Loop initiative, the UK’s first BioFactory will be established to analyse waste streams and scale up new, circular biomanufacturing processes.

Shaping a sustainable manufacturing future

These hubs are two of four new national centres funded through EPSRC’s Manufacturing Research Hubs for a Sustainable Future programme, designed to catalyse the UK’s transition to cleaner, more resilient manufacturing.

Professor Charlotte Deane, Executive Chair of EPSRC, commented

“These hubs will play a vital role in reshaping manufacturing to help the UK achieve green growth. By combining deep research expertise with real-world partnerships, they will develop the technologies, tools and systems we need for clean, competitive and resilient industries.”

ֱ’s dual role across both hubs highlights its cross-disciplinary leadership in sustainability and its commitment to pioneering innovations that support green growth, circular economy practices, and industrial transformation across the UK.

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Thu, 19 Jun 2025 10:44:43 +0100 https://content.presspage.com/uploads/1369/8b33a626-1c18-478f-b57a-ed50618195ab/500_edinburghgenomefoundry.creditedinburghinnovationsandmaverickphotography.jpg?10000 https://content.presspage.com/uploads/1369/8b33a626-1c18-478f-b57a-ed50618195ab/edinburghgenomefoundry.creditedinburghinnovationsandmaverickphotography.jpg?10000
Manchester-led study identifies fair paths to net zero for developing countries /about/news/manchester-led-study-identifies-fair-paths-to-net-zero-for-developing-countries/ /about/news/manchester-led-study-identifies-fair-paths-to-net-zero-for-developing-countries/711586New research led by ֱ has outlined a more equitable way to plan the transition to low-carbon energy systems that reduces regional disparities in access to energy and water services.

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New research led by ֱ has outlined a more equitable way to plan the transition to low-carbon energy systems that reduces regional disparities in access to energy and water services.

As nations around the world aim to meet climate targets set by the Paris Agreement, the researchers highlight that without careful planning, effort to cut emissions could unintentionally maintain or widen existing regional gaps in access to services, such as how energy and water are distributed.

To help address this, the team have developed a framework, published in the journal , which uses artificial intelligence tools combined with detailed country-scale digital twin simulators to help identify infrastructure intervention plans that reduce emissions while fairly managing access to vital services like electricity and water, and improving food production.

The approach aims to help achieve sustainability and climate targets, particularly in countries with complicated interdependencies between sectors and inequitable access to services. It helps ensure that no region or community is left behind in the journey to net zero and supports UN Sustainable Development Goals.

Using a case study of Ghana, the research shows that reaching a fairer, low-carbon energy transition will not only require increased investments in renewable energy and transmission infrastructure but also more informed social, economic, and environmental planning. Countries must consider who benefits from infrastructure investments – not just how much carbon they cut.

This research was published in the journal Nature Communications.

Full title: Delivering equity in low-carbon multisector infrastructure planning

DOI:

Link:

Our research is at the forefront of the energy transition. Guided by our innovative spirit and interdisciplinary outlook, we work to mitigate climate change while transforming our energy system, to enable a just and prosperous future for all. Find out more about our energy research. 

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Professor Patrick Cai elected to the Academia Europaea /about/news/professor-patrick-cai-elected-to-the-academia-europaea/ /about/news/professor-patrick-cai-elected-to-the-academia-europaea/708514We are pleased to announce that from the has been elected to the , one of Europe’s most distinguished academic institutions. This honour recognises his exceptional contributions to the fields of synthetic biology, genome engineering, and interdisciplinary research across Europe and beyond.

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, and home to the , we are focused on finding new and more sustainable ways to produce chemicals, materials, and everyday products, by understanding and harnessing nature’s own processes and applying them at industrial scales. Find out more via our .

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Patrick’s election into the academy reflects his efforts to develop advanced methods for understanding and engineering biological systems. His work bridges molecular biology, chemistry, and computational design, with a focus on building the tools and infrastructure that enable innovation in biotechnology, it also recognises his leadership in fostering international collaboration and responsible research.

Chief among his international work is his involvement in the , a collaborative research network involving leading universities from Europe, North America, and Asia. This initiative, praised by Nature as a model for global collaboration, provides a platform for researchers to explore fundamental biological questions and develop tools with wide-ranging applications.

From this project Patrick was a key figure in the development of Europe’s first synthetic yeast chromosome, which serves as a platform for studying genome function and organisation. Rather than constructing life from scratch, this work aims to provide researchers with better ways to investigate how genetic systems behave, evolve, and can be adapted for beneficial use.

Alongside this he is recognised for his involvement in the founding of the , Europe’s first and largest facility for DNA synthesis and assembly. The Foundry has become a cornerstone of research infrastructure, enabling scientists across disciplines to design and test new biological components more efficiently and reliably.

Patrick’s research is firmly focused in advancing knowledge, improving safety, and supporting applications in areas such as medicine, sustainable production, and global health. He recognises the need for his work to be grounded in social responsibility and regularly contributes to global policy discussions on biosecurity. He is a respected advisor to bodies including the United Nations and the UK government and his work on safety and governance helps guide the responsible development of emerging biotechnologies.

With over 80 peer-reviewed publications, numerous awards, and academic appointments at institutions such as MIT and the University of Cambridge, Patrick continues to shape the future of life sciences. His election to the Academia Europaea is a well-deserved recognition of his interdisciplinary achievements, international leadership, and commitment to advancing science in the public interest.

We extend our sincere congratulations to Patrick on this significant honour.

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Wed, 18 Jun 2025 14:30:18 +0100 https://content.presspage.com/uploads/1369/ffbfeef3-5faf-48c2-8523-a7c9432904f7/500_patrick-cai-cr.davephillips-lede-2048x1152.png?10000 https://content.presspage.com/uploads/1369/ffbfeef3-5faf-48c2-8523-a7c9432904f7/patrick-cai-cr.davephillips-lede-2048x1152.png?10000
GEIC Engineering Director joins 2DMoT CDT Advisory Board /about/news/geic-engineering-director-joins-2dmot-cdt-advisory-board/ /about/news/geic-engineering-director-joins-2dmot-cdt-advisory-board/711363John Whittaker, Engineering Director at the Graphene Engineering Innovation Centre (GEIC), is delighted to announce his appointment to the international advisory board of the EPSRC Centre for Doctoral Training in 2D Materials of Tomorrow (2DMoT CDT). 

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John Whittaker, Engineering Director at the , is delighted to announce his appointment to the international advisory board of the EPSRC Centre for Doctoral Training in 2D Materials of Tomorrow (2DMoT CDT). The new CDT builds on the legacy of ֱ’s pioneering Graphene NOWNANO CDT and is designed to shape the next generation of leaders in the fast-evolving field of 2D materials.

Reflecting on his new role John said, “It’s a real privilege to be part of this initiative. The 2DMoT CDT doesn’t just focus on academic excellence - it brings research to life by connecting it with industry, impact, and innovation. I’m excited to work alongside these emerging researchers and help create a space where science and real-world application go hand in hand.”

Funded by the EPSRC, the 2DMoT CDT will welcome its first student cohort in September 2025. The programme is a collaboration between ֱ and the University of Cambridge, with initial training and the majority of research projects based in Manchester. The CDT offers an intensive four-year PhD that focuses on the science and application of the rapidly growing family of two-dimensional (2D) materials. It provides a unique training environment that blends academic excellence with industry collaboration and innovation opportunities.

The CDT aligns closely with the Faculty of Science and Engineering (FSE)’s vision and the University’s ambition to define the role of a great civic university in the 21st century. Advanced materials is one of FSE’s core research beacons, and the CDT builds on this by promoting employability, interdisciplinary training, and values-driven partnerships. Rooted in innovation and a strong sense of purpose, the programme reflects our commitment to global impact, local engagement, and an inclusive student experience.

This vision is brought to life through the work of the GEIC, where John serves as Engineering Director. As one of the UK’s leading centres for the commercialisation of 2D materials, the GEIC transforms early-stage research into real-world applications, helping businesses navigate the crucial ‘middle ground’ of technology readiness (TRLs 4–7). With its state-of-the-art infrastructure, industrial partnerships, and translational focus, the GEIC plays a central role in the advanced materials ecosystem. John’s involvement in the CDT advisory board strengthens the pipeline between research and industry - ensuring doctoral students gain not only technical excellence, but the commercial awareness needed to drive innovation from lab to market.

The CDT’s impact also extends into Manchester’s wider innovation landscape through Unit M - a bold, University-led initiative to accelerate discovery, innovation, and inclusive economic growth. Unit M connects research, industry, investors, and civic partners to unlock the full potential of the region’s innovation ecosystem. By developing skilled researchers and fostering academic–industry collaboration, the CDT plays a valuable role in supporting Unit M’s mission to drive prosperity across Greater Manchester and beyond.

This collaborative spirit is further exemplified by the new Manchester–Cambridge partnership, with the CDT as one of its early flagship initiatives. By linking two of the UK’s most dynamic innovation economies, the partnership brings together Manchester’s strengths in industry-facing innovation with Cambridge’s academic excellence and world-class startup culture. Together, they represent a new model for university collaboration – one rooted in purpose, people, and place – that challenges traditional boundaries and redefines what’s possible when research, talent, and enterprise move hand in hand.

As John steps into this advisory role, his appointment is a reflection not only of his leadership at GEIC but of the broader vision to ensure that materials science remains one of the UK’s greatest engines of innovation.

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Advancing renewable energy-powered solutions for water desalination /about/news/advancing-renewable-energy-powered-solutions-for-water-desalination/ /about/news/advancing-renewable-energy-powered-solutions-for-water-desalination/711038ֱ is part of the EU-funded AQUASOL project, working to address global water scarcity through renewable energy-powered desalination. Researchers at Manchester will develop graphene-based membranes designed to treat seawater and brackish water more efficiently. The goal is to increase membrane durability and reduce energy demands, offering practical improvements over current desalination systems.

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The University of Manchester is part of the EU-funded project, working to address global water scarcity through renewable energy-powered desalination.

Desalination of seawater and brackish water is one of the essential solutions to the increasing global challenge of water scarcity. Yet, widespread deployment of desalination technologies remains limited due to high upfront costs and intensive energy requirements. Moreover, current desalination systems use fossil fuels contributing to greenhouse gas emissions.

To address these challenges, the EU-funded project AQUASOL brings together a multidisciplinary team of seven partners from six countries to explore and develop innovative solutions to facilitate green transition in desalination processes. To achieve this, the consortium will develop a technological platform that will enable the integration of renewable energy sources into desalination technologies and provide disruptive solutions for seawater and wastewater treatment.

, a researcher at Manchester, will develop graphene-based membranes designed to treat seawater and brackish water more efficiently. The goal is to increase membrane durability and reduce energy demands, offering practical improvements over current desalination systems.

The partners, comprising of research institutions, universities and small and medium businesses, met in Barcelona to officially launch the project, which started earlier this month.

AQUASOL, which stands for Advanced Quality Renewable Energy-Powered Solutions For Water Desalination In Agriculture And Wastewater Recycling, has a total budget of over €3.6M and will run for 3 years. ֱ joins six other partners: Instituto Tecnológico de Canarias (Spain), Strane Innovation (France), Ferr-Tech B.V. (Netherlands), farmB (Greece), and Aarhus University (Denmark).

 

Acknowledgements

Funded by the European Union. Views and opinions expressed are however those of the author(s) only and do not necessarily reflect those of the European Union or European Research Executive Agency (REA). Neither the European Union nor the granting authority can be held responsible for them.

We’re home to 700 materials experts, revolutionising industries by developing advanced materials that unlock new levels of performance, efficiency, and sustainability. Supported by the £885m campus investment over the last 10 years, our researchers are at the forefront of materials innovation, creating game-changing solutions. From healthcare to manufacturing, we’re tackling global challenges and ensuring the UK's reputation as a technology ‘super power'. Find out more about our advanced materials research.

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Tue, 17 Jun 2025 14:38:58 +0100 https://content.presspage.com/uploads/1369/815585e4-66e9-44fb-9378-3ff74e6e36d8/500_1-3.jpg?10000 https://content.presspage.com/uploads/1369/815585e4-66e9-44fb-9378-3ff74e6e36d8/1-3.jpg?10000
Manchester researchers design 2D lattice to extend zinc-ion battery life /about/news/manchester-researchers-design-2d-lattice-to-extend-zinc-ion-battery-life/ /about/news/manchester-researchers-design-2d-lattice-to-extend-zinc-ion-battery-life/710925Scientists from the at ֱ and the University of Technology Sydney have developed a new way to improve the lifespan of zinc-ion batteries, offering a safer and more sustainable option for energy storage.

The team designed a two-dimensional (2D) manganese-oxide/graphene superlattice that triggers a unique lattice-wide strain mechanism. This approach significantly boosts the structural stability of the battery’s cathode material, enabling it to operate reliably over 5,000 charge-discharge cycles. That’s around 50% longer than current zinc-ion batteries.

The research, published in , offers a practical route to scalable, water-based energy storage technologies.

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Scientists from the at ֱ and the University of Technology Sydney have developed a new way to improve the lifespan of zinc-ion batteries, offering a safer and more sustainable option for energy storage.

The team designed a two-dimensional (2D) manganese-oxide/graphene superlattice that triggers a unique lattice-wide strain mechanism. This approach significantly boosts the structural stability of the battery’s cathode material, enabling it to operate reliably over 5,000 charge-discharge cycles. That’s around 50% longer than current zinc-ion batteries.

The research, published in , offers a practical route to scalable, water-based energy storage technologies.

 

Atomic-level control over battery durability

The breakthrough centres on a phenomenon called the Cooperative Jahn-Teller Effect (CJTE). A coordinated lattice distortion caused by a specific 1:1 ratio of manganese ions (Mn³ and Mn⁴⁺). When built into a layered 2D structure on graphene, this ratio produces long-range, uniform strain across the material.

2D lattice

That strain helps the cathode resist breakdown during repeated cycling.

The result is a low-cost, aqueous zinc-ion battery that performs with greater durability, and without the safety risks linked to lithium-ion cells.

“This work demonstrates how 2D material heterostructures can be engineered for scalable applications,” said , lead and corresponding author from University of Technology Sydney and a Royal Society Wolfson visiting Fellow at ֱ. “Our approach shows that superlattice design is not just a lab-scale novelty, but a viable route to improving real-world devices such as rechargeable batteries. It highlights how 2D material innovation can be translated into practical technologies.”

 

Towards better grid-scale storage

Zinc-ion batteries are widely viewed as a promising candidate for stationary storage, storing renewable energy for homes, businesses or the power grid. But until now, their limited lifespan has restricted real-world use.

This study shows how chemical control at the atomic level can overcome that barrier.

Co-corresponding author from ֱ said, “Our research opens a new frontier in strain engineering for 2D materials. By inducing the cooperative Jahn-Teller effect, we’ve shown that it’s possible to fine-tune the magnetic, mechanical, and optical properties of materials in ways that were previously not feasible.”

The team also demonstrated that their synthesis process works at scale using water-based methods, without toxic solvents or extreme temperatures - a step forward in making zinc-ion batteries more practical for manufacturing.

 

This research was published in the journal Nature Communications.

Full title: Cooperative Jahn-Teller effect and engineered long-range strain in manganese oxide/graphene superlattice for aqueous zinc-ion batteries

DOI: 

We’re home to 700 materials experts, revolutionising industries by developing advanced materials that unlock new levels of performance, efficiency, and sustainability. Supported by the £885m campus investment over the last 10 years, our researchers are at the forefront of materials innovation, creating game-changing solutions. From healthcare to manufacturing, we’re tackling global challenges and ensuring the UK's reputation as a technology ‘super power'. Find out more about our advanced materials research.

The is a world-leading graphene and 2D material centre, focussed on fundamental research. Based at ֱ, where graphene was first isolated in 2004 by Professors Sir Andre Geim and Sir Kostya Novoselov, it is home to leaders in their field – a community of research specialists delivering transformative discovery. This expertise is matched by £13m leading-edge facilities, such as the largest class 5 and 6 cleanrooms in global academia, which gives the NGI the capabilities to advance underpinning industrial applications in key areas including: composites, functional membranes, energy, membranes for green hydrogen, ultra-high vacuum 2D materials, nanomedicine, 2D based printed electronics, and characterisation.

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Mon, 16 Jun 2025 10:00:00 +0100 https://content.presspage.com/uploads/1369/cc23bf14-626e-4d01-b77d-3bac1d4748ad/500_jw-nationalgrapheneinstitute-visit1---laquohuftoncrow-015.jpg?10000 https://content.presspage.com/uploads/1369/cc23bf14-626e-4d01-b77d-3bac1d4748ad/jw-nationalgrapheneinstitute-visit1---laquohuftoncrow-015.jpg?10000
Breakthrough in quantum materials: UK Scientists achieve precision activation of quantum defects in diamond /about/news/breakthrough-in-quantum-materials-uk-scientists-achieve-precision-activation-of-quantum-defects-in-diamond/ /about/news/breakthrough-in-quantum-materials-uk-scientists-achieve-precision-activation-of-quantum-defects-in-diamond/711809A new study led by researchers at the Universities of Oxford, Cambridge and Manchester has achieved a major advance in quantum materials, developing a method to precisely engineer single quantum defects in diamond—an essential step toward scalable quantum technologies. 

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A new study led by researchers at the Universities of Oxford, Cambridge and Manchester has achieved a major advance in quantum materials, developing a method to precisely engineer single quantum defects in diamond—an essential step toward scalable quantum technologies. 

The results have been published in the journal .

Using a new two-step fabrication method, the researchers demonstrated for the first time that it is possible to create and monitor, ‘as they switch on’, individual Group-IV quantum defects in diamond—tiny imperfections in the diamond crystal lattice that can store and transmit information using the exotic rules of quantum physics. By carefully placing single tin atoms into synthetic diamond crystals and then using an ultrafast laser to activate them, the team achieved pinpoint control over where and how these quantum features appear. This level of precision is vital for making practical, large-scale quantum networks capable of ultra-secure communication and distributed quantum computing to tackle currently unsolvable problems.

ֱ co-author , Department of Materials at the University of Oxford, said: “This breakthrough gives us unprecedented control over single tin-vacancy colour centres in diamond, a crucial milestone for scalable quantum devices. What excites me most is that we can watch, in real time, how the quantum defects are formed.”

Specifically, the defects in the diamond act as spin-photon interfaces, which means they can connect quantum bits of information (stored in the spin of an electron) with particles of light. The tin-vacancy defects belong to a family known as Group-IV colour centres—a class of defects in diamond created by atoms such as silicon, germanium, or tin.

Group-IV centres have long been prized for their high degree of symmetry, which gives them stable optical and spin properties, making them ideal for quantum networking applications. It is widely thought that tin-vacancy centres have the best combination of these properties—but until now, reliably placing and activating individual defects was a major challenge.

The researchers used a focused ion beam platform—essentially a tool that acts like an atomic-scale spray can, directing individual tin ions into exact positions within the diamond. This allowed them to implant the tin atoms with nanometre accuracy—far finer than the width of a human hair.

To convert the implanted tin atoms to tin-vacancy colour centres, the team then used ultrafast laser pulses in a process called laser annealing. This process gently excites tiny regions of the diamond without damaging it. What made this approach unique was the addition of real-time spectral feedback—monitoring the light coming from the defects during the laser process. This allowed the scientists to see in real time when a quantum defect became active and adjust the laser accordingly, offering an unprecedented level of control over the creation of these delicate quantum systems.

ֱ co-author  from the University of Cambridge, said: “What is particularly remarkable about this method is that it enables in-situ control and feedback during the defect creation process. This means we can activate quantum emitters efficiently and with high spatial precision - an important tool for the creation of large-scale quantum networks. Even better, this approach is not limited to diamond; it is a versatile platform that could be adapted to other wide-bandgap materials.”

Moreover, the researchers observed and manipulated a previously elusive defect complex, termed “Type II Sn”, providing a deeper understanding of defect dynamics and formation pathways in diamond.

ֱ co-author , Professor of Advanced Electronic Materials at ֱ, said: “This work unlocks the ability to create quantum objects on demand, using methods that are reproducible and can be scaled up. This is a critical step in being able to deliver quantum devices and allow this technology to be utilised in real-world commercial applications.”

The study ‘Laser Activation of Single Group-IV Colour Centres in Diamond’ has been published in Nature Communications

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Mon, 16 Jun 2025 09:29:00 +0100 https://content.presspage.com/uploads/1369/594546d6-e624-4d65-a948-4f03843bd880/500_quantum-siliconstory-1.jpg?10000 https://content.presspage.com/uploads/1369/594546d6-e624-4d65-a948-4f03843bd880/quantum-siliconstory-1.jpg?10000
Manchester debuts at Europe’s largest laboratory animal event /about/news/manchester-debuts-at-europes-largest-laboratory-animal-event/ /about/news/manchester-debuts-at-europes-largest-laboratory-animal-event/710876ֱ's Biological Services Facility has debuted at Europe's most significant laboratory animal science gathering.

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ֱ's Biological Services Facility has debuted at Europe's most significant laboratory animal science gathering. 

Over 2000 scientists, veterinarians, technicians, and regulators from across Europe and beyond converged on Athens for the sixteenth FELASA Congress to hear BSF Director Dr Maria Kamper’s vision on transformational leadership. 

The Congress is held every three years in different European cities to advance excellence in laboratory animal science. 

FELASA - the Federation of European Laboratory Animal Science Associations - develops guidelines and policies on all aspects of laboratory animal science, including training programs, welfare standards, and scientific best practice. 

Representing professionals in over 28 countries across Europe, this year's Congress took place between June 2 and 5 at the Megaron Athens International Conference Centre. 

Dr Maria Kamper, Director of the BSF, spoke to a packed audience about how exceptional leadership creates excellence in laboratory animal science.

 Drawing from her philosophy that "people are the heart of our work," Dr Kamper challenged the traditional approach to facility management. 

"We don't just ask our staff to follow protocols," Dr Kamper told the Congress. "We inspire them to see themselves as guardians of breakthrough discoveries. 

“Every refinement they create could spare suffering for thousands of animals. They go to work knowing they are advancing human knowledge while honouring every heartbeat in their care," she added. 

The BSF's Dr Jo Stanley and Mike Addelman from the University's Directorate of Communications, Marketing and Student Recruitment also addressed the Congress on the University's sector-leading openness agenda in animal research. 

The University - officially recognized as a Leader in Openness - has developed an award-winning website and engagement programme that has become a trailblazer for the sector, demonstrating how transparency fosters public trust, enhances research integrity, promotes collaboration, and exemplifies ethical rigor in the responsible use of animals in research. 

Dr Kamper said: "Being part of FELASA was an extraordinary privilege and represents the kind of strategic leadership that looks beyond daily operations toward future possibilities.

“We are proud of the culture of excellence we have cultivated at Manchester - where our teams don't just meet standards, they set new ones.

 “Our hope is that the transformational approach we've developed here will inspire colleagues across Europe and beyond to lead their teams toward excellence that serves both scientific advancement and compassionate animal care.” 

  • Dr Stanley's attendance was supported by a LASA (Laboratory animal science association) bursary
  • To view the presentation by Dr Kamper, click
  • To view the presentation by Dr Stanley and Mike Addelman click
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Fri, 13 Jun 2025 09:00:00 +0100 https://content.presspage.com/uploads/1369/74ef67e5-eca1-4497-890e-f4ef03caf8e7/500_felasalogo.png?10000 https://content.presspage.com/uploads/1369/74ef67e5-eca1-4497-890e-f4ef03caf8e7/felasalogo.png?10000
University scientist named finalist for prestigious AI award /about/news/university-scientist-named-finalist-for-prestigious-ai-award/ /about/news/university-scientist-named-finalist-for-prestigious-ai-award/708747An academic and a corresponding team from ֱ have been announced as finalists for the acclaimed Manchester Prize.   

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An academic and a corresponding team from ֱ have been announced as finalists for the acclaimed Manchester Prize.   

, Reader in Engineering for Net Zero, is one of ten finalists to be awarded £100,000 in seed funding to develop his solution for this year’s .  

In its second year, the Manchester Prize is looking for researchers with the most impactful and innovative artificial intelligence (AI) solution enabling the UK to accelerate progress towards net zero.  

Although AI technologies are advancing rapidly, their adoption in clean energy systems has not kept pace. The Manchester Prize aims to accelerate progress by encouraging the development of AI solutions that support the UK in achieving its ambition to lead the world in clean energy. 

Dr Papadopoulos’ solution, Grid Stability, uses AI to accelerate the analysis performed which ensures electrical power systems meet the specified stability, security and reliability criteria. 

Electrical power systems worldwide are going through unprecedented changes to achieve decarbonisation targets. This drive calls for new technologies, such as renewables, electric vehicles and heat pumps, which increases the complexity and uncertainty in power system operation. System stability is the cornerstone of power system operation, and if not carefully considered, it can lead to blackouts with high economic impact and fallout.  

The tool replaces slow, complex simulations with rapid, AI-driven assessments, enabling real-time monitoring, faster decision-making, and more confident planning. This helps grid operators maintain reliability while scaling up clean energy solutions and cutting emissions. 

Dr Papadopoulos aims to work closely with utility companies to enable safe and useful implementations of Grid Stability. 

Speaking about his solution, Dr Papadopoulos said: “Grid Stability uses machine learning to help bring lower, or zero, carbon technologies onto the grid faster and at the scale we need to hit net zero, but without compromising system stability.

Being named a finalist for the Manchester Prize is a huge boost; it not only validates the impact of our work but also gives us a platform to accelerate progress and collaborate more widely across the energy sector.”

Dr Papadopoulos recognised that the computational cost and complexity of assessing stability and security made it difficult to support real-time awareness, decision-making and optimisation. As a result, system dynamics are often neglected or oversimplified. Grid Stability, using machine learning, offers a promising solution to addressing this challenge. 

The Manchester Prize will pick its winner in Spring 2026, and the winning innovator will receive a £1 million grand prize to continue developing their solution. The winning solution must demonstrate not only technical innovation, but also an evidenced road map to near-term (2030) adoption and scale.  

Announced and launched in 2023, the Manchester Prize is multi-million-pound, multi-year challenge prize, which is funded by the Department of Science, Innovation and Technology. The Prize seeks to reward UK-led breakthroughs in AI for public good and continues to secure the UK’s place as a global leader in cutting-edge innovation. 

The Manchester Prize is named after the world’s first stored programme computer, nicknamed ‘The Baby’, which was built at ֱ in 1948. AI research at The University continues to build on this legacy, as shown by Dr Papadopoulos’ achievement. 

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Wed, 11 Jun 2025 09:00:00 +0100 https://content.presspage.com/uploads/1369/69aa8140-fb28-4743-b14f-b2d66df84349/500_2025-05-29-challengeworksmanchesterprize-26edited.jpg?10000 https://content.presspage.com/uploads/1369/69aa8140-fb28-4743-b14f-b2d66df84349/2025-05-29-challengeworksmanchesterprize-26edited.jpg?10000
Construction emerges as major source of black carbon in central London /about/news/construction-emerges-as-major-source-of-black-carbon-in-central-london/ /about/news/construction-emerges-as-major-source-of-black-carbon-in-central-london/708611New research has revealed that construction activity is now a dominant source of black carbon emissions in central London.

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New research has revealed that construction activity is now a dominant source of black carbon emissions in central London.

While pollution levels from road traffic have fallen significantly thanks to policies like the Ultra Low Emission Zone (ULEZ), new air pollution data from scientists at ֱ, in collaboration with the UK Centre for Ecology & Hydrology (UKCEH), University of York, Zhejiang University and National Centre for Atmospheric Science, reveal emissions from non-road mobile machinery, such as generators and heavy-duty construction equipment, can exceed those from vehicles, particularly in areas where there is a lot of building activity.

Black carbon is soot from combustion and is a component of particulate matter (PM2.5). These are very fine particles that can enter the lungs and bloodstream and are known to damage human health. 

The team collected the pollution measurements from the top of the BT Tower in central London over summer and winter, using a technique called eddy covariance to track how much black carbon is released into the air and where it comes from.

The findings revealed that while pollution levels were significantly lower than cities like Beijing and Delhi, who have monitored pollution using the same method, they are not low enough to meet the . They suggest similar regulatory attention to road traffic is now needed for the construction sector. 

The study, published in the journal is the first of its kind in Europe.

At 190 metres tall, the BT Tower observatory has a specialised gas inlet system installed on the tower’s roof, which draws air into a laboratory on the 35th floor, allowing researchers to analyse pollution as it rises from streets, buildings, construction sites and nearby parks below.

The ‘eddy covariance’ method works by measuring the turbulent motion of air, also known as eddies, and the concentration of airborne substances like black carbon within those eddies.

The scientists also conducted a detailed spatial footprint analysis to pinpoint emission hotspots that were directly linked to active construction sites near the BT Tower.

The new findings suggest that further progress in improving London’s air quality will require stricter regulation of construction machinery, especially in rapidly developing areas.

added: “We compared observed emissions with emission standards for construction equipment and found that even with compliance, black carbon output from generators, machinery and construction vehicles remains significant. Our work highlights how measurement techniques like eddy covariance can fill critical gaps in our understanding of urban pollution and support evidence-based strategies to protect public health and the environment.”

This research was published in the journal Environmental Sciences: Atmospheres

Full title: Quantifying black carbon emissions from traffic and construction in central London using eddy covariance

DOI:

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Fri, 06 Jun 2025 09:17:24 +0100 https://content.presspage.com/uploads/1369/78b1721e-48b6-4c38-9501-0c8c66680868/500_bttowerlondon.photobyjoshwithershttpswww.pexels.comphotobt-tower-london-uk-17092032.jpg?10000 https://content.presspage.com/uploads/1369/78b1721e-48b6-4c38-9501-0c8c66680868/bttowerlondon.photobyjoshwithershttpswww.pexels.comphotobt-tower-london-uk-17092032.jpg?10000
Earth’s mantle gases found seeping into groundwater far from volcanic zones /about/news/earths-mantle-gases-found-seeping-into-groundwater-far-from-volcanic-zones/ /about/news/earths-mantle-gases-found-seeping-into-groundwater-far-from-volcanic-zones/708485Scientists have uncovered new evidence to suggest that Earth is leaking gases from deep inside its mantle - even in regions without any volcanic activity.

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Scientists have uncovered new evidence to suggest that Earth is leaking gases from deep inside its mantle - even in regions without any volcanic activity.

Led by researchers at ֱ, the study reveals that invisible, odourless gases like helium and argon are slowly seeping hundreds of kilometres up through Earth’s crust, reaching underground water supplies thousands of meters beneath our feet.

For decades, scientists have believed that the vast majority of Earth’s internal gases are either pushed deep underground through tectonic activity, or escape back to the surface through volcanic eruptions.

The new research, published in the journal , challenges this understanding  and the findings could give scientists a better idea of the geological and chemical processes that take place deep inside the Earth.

“Think of it like a having small puncture in your car tyre,” said lead author Dr Rebecca Tyne, Dame Kathleen Ollerenshaw Fellow at ֱ.

“We’ve discovered a steady trickle of gases coming from deep within Earth, even though there’s no obvious volcanic activity on the surface.

“This passive degassing of the mantle may be an important, yet previously unrecognised process and these findings will help our understanding of how our planet’s interior works  and how much gas is escaping into the atmosphere over time. It could even play an important role in the geologic carbon cycle”

The researchers analysed groundwater from 17 wells in the Palouse Basin Aquifer in the United States - a key source of drinking water in a region considered to be geologically stable.

Using advanced measurement techniques, they measured for multiple types of helium and argon and found signatures to suggest these gases had travelled up from the Earth’s mantle — the hot, dense layer between the outer crust and the core. Importantly, the helium and argon gases detected are inert, meaning they do not react chemically or affect water quality.

Co-author Dr Mike Broadley , NERC Independent Research Fellow at ֱ, said: “We found evidence of mantle-derived gasses in 13 out of the 17 wells.  These gases – especially helium-3 and argon-40 – do not form in the atmosphere or in shallow rocks, they come from a layer of the mantle called the sub-continental lithospheric mantle, many kilometres deep in the Earth.”

The highest amount of gas was found in the oldest and deepest groundwater samples - some over 20,000 years old - indicating the gases have been moving slowly but steadily over a long period of time.

The researchers also found a strong correlation between the samples, suggesting they are travelling up together from the same deep source.

Their findings suggest that this kind of low-level, non-volcanic degassing may be more common – and more important – than previously thought. The team are now planning to investigate whether this is a globally consistent phenomenon by investigating groundwaters worldwide.

The research was carried out in collaboration with Woods Hole Oceanographic Institution (USA),  Université de Lorraine (France), University of Ottawa (Canada) and the University of Idaho (USA).

Journal: Nature Geoscience

Full title: Passive degassing of lithospheric volatiles recorded in shallow young groundwater

DOI: 10.1038/s41561-025-01702-7

Link:

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Thu, 05 Jun 2025 10:00:00 +0100 https://content.presspage.com/uploads/1369/b1d0949f-7e3e-406a-9c8b-c02d0bd6562a/500_2f7efa1b-a469-41c8-b7c6-852bf66369de.jpeg?10000 https://content.presspage.com/uploads/1369/b1d0949f-7e3e-406a-9c8b-c02d0bd6562a/2f7efa1b-a469-41c8-b7c6-852bf66369de.jpeg?10000
World-best measurements made in mission to crack muon mystery /about/news/world-best-measurements-made-in-mission-to-crack-muon-mystery/ /about/news/world-best-measurements-made-in-mission-to-crack-muon-mystery/708492Manchester scientists have played a key role in achieving the world’s most precise measurement of a mysterious property of the muon, a subatomic particle that could help reveal new physics beyond our current understanding.

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Manchester scientists have played a key role in achieving the world’s most precise measurement of a mysterious property of the muon, a subatomic particle that could help reveal new physics beyond our current understanding.

The breakthrough, , the U.S. Department of Energy’s Fermi National Accelerator Laboratory, brings researchers one step closer to discovering forces or particles beyond the Standard Model of physics.

This result represents the most precise measurement ever made at a particle accelerator anywhere in the world, and could help unlock the secrets of the universe.

What is the Muon g-2 Experiment?

The Muon g-2 experiment investigates the subtle “wobble” in the motion of muons, particles similar to electrons but with 200 times more mass, as they move through a magnetic field.

This wobble, known as the muon’s ‘anomalous magnetic moment’, or g-2, provides one of the most sensitive and precise tests of the Standard Model of particle physics, the theory that explains how fundamental particles and forces interact.

Landmark results

This announcement reveals the experiment’s third and final measurement, which confirms earlier results, but with a much better precision of 127 parts-per-billion, surpassing the original experimental design goal of 140 parts-per-billion.

These results now stand as the world’s most accurate measurement of the muon magnetic anomaly.

Representing more than a decade of work, this milestone is expected to stand as the definitive benchmark for testing the Standard Model for years to come.

Critical UK contribution

Scientists from the Universities of Manchester, Lancaster, Liverpool, and University College London were central to the experiment, which brought together 176 researchers from 34 institutions across seven countries.

The UK-built straw tracking detectors were essential in tracing the motion of the muon beam, a critical part of the analysis that enabled this unprecedented level of precision.

ֱ was responsible for mapping the vertical oscillations in the beam motion using the detectors and in the theory prediction for the measured value.

Professor Mark Lancaster, Principle Investigator of the UK groups from ֱ, said: “This is the most precise measurement ever made at a particle accelerator and the culmination of over a decade’s work. The motion of the muon beam was exquisitely traced by the UK-built straw tracking detectors and was a key part of the analysis. That we now have a measurement to a precision of 0.1 parts per million and a theoretical prediction, to 0.5 parts per million, is a remarkable achievement from the work of hundreds of people.”

STFC’s Professor Sinead Farrington, Director of Particle Physics, added: “What’s really fascinating about this result is the way it has illustrated the interplay between theoretical predictions and experimental results - each can lead the other, and make demands on the precision of the other.  

“The UK has played critical roles of which we can be proud, both in leadership and in developing the straw tracking detectors, in this highly international collaboration.”

Read the at the Fermilab website.

ֱ is globally renowned for its pioneering research, outstanding teaching and learning, and commitment to social responsibility. We are a truly international university – ranking in the top 50 in a range of global rankings – with a diverse community of more than 44,000 students, 12,000 staff and 550,000 alumni from 190 countries.  Sign up for our e-news to hear first-hand about our international partnerships and activities across the globe. 

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Thu, 05 Jun 2025 09:32:50 +0100 https://content.presspage.com/uploads/1369/500_muong-2magnetcreditreidarhahnfermilabmuong2collaboration.jpeg?10000 https://content.presspage.com/uploads/1369/muong-2magnetcreditreidarhahnfermilabmuong2collaboration.jpeg?10000
Scientists make first direct observation of the trapped waves that shook the world /about/news/scientists-make-first-direct-observation-of-the-trapped-waves-that-shook-the-world/ /about/news/scientists-make-first-direct-observation-of-the-trapped-waves-that-shook-the-world/708254Researchers have used cutting-edge satellite technology to shed light on the global mystery of the unexplained seismic signals that “shook the Earth” for nine days.

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Researchers have used cutting-edge satellite technology to shed light on the global mystery of the unexplained seismic signals that “shook the Earth” for nine days.

In September 2023, scientists observed a bizarre series of global seismic signals, which appeared every 90 seconds over nine days – and then repeated a month later.

Almost a year later, two scientific studies proposed that the cause of these seismic anomalies were two mega tsunamis which were triggered in a remote East Greenland fjord by two major landslides which occurred due to warming of an unnamed glacier. The waves were thought to have become trapped in the fjord system, forming standing waves (or seiches) that undulated back and forth, causing the mystery signals.

Until now, there have been no observations of these seiches to confirm this theory.

Now, using a brand-new type of satellite altimetry, a team of researchers have confirmed the theory and provided the first observations of these waves whose behaviour is entirely unprecedented.

The new research is published today in the journal .

, Lecturer in Fluid Mechanics at ֱ, who carried out the research in Oxford, said: “It's impressive to see that machine learning plays an important role in identifying these trapped waves. This research demonstrates how advancements in technology are enabling new observations and datasets, and also importantly, changing our approach to extracting scientific insights from large-scale data.”

Using data from the Surface Water and Ocean Topography (SWOT) satellite, the research team were able to capture the wave activity for the first time. SWOT launched in December 2022 to map the height of water across 90% of Earth’s surface. It is equipped with the cutting-edge Ka-band Radar Interferometer (KaRIn) instrument, which uses two antennas to measure ocean and surface water levels across a swath 30 miles wide.

The researchers then made elevation maps of the Greenland Fjord at various time points following the two tsunamis. These showed clear, cross-channel slopes with height differences of up to two metres. Crucially, the slopes in these maps occurred in opposite directions, showing that water moved backwards and forwards across the channel.

To validate their findings, the researchers linked these observations to small movements in the Earth’s crust recorded thousands of kilometres away, allowing them to reconstruct the characteristics of the wave, even for periods which the satellite did not observe. They also reconstructed weather and tidal conditions to rule out alternative explanations such as wind or tides.

Lead author (DPhil student, Department of Engineering Science, University of Oxford) said: “Climate change is giving rise to new, unseen extremes. These extremes are changing the fastest in remote areas, such as the Arctic, where our ability to measure them using physical sensors is limited. This study shows how we can leverage the next generation of satellite earth observation technologies to study these processes.

“SWOT is a game changer for studying oceanic processes in regions, such as fjords, which previous satellites struggled to see into.”

Co-author (Department of Engineering Science, University of Oxford) said: “This study is an example of how the next generation of satellite data can resolve phenomena that has remained a mystery in the past. We will be able to get new insights into ocean extremes such as tsunamis, storm surges, and freak waves. However, to get the most out of these data we will need to innovate and use both machine learning and our knowledge of ocean physics to interpret our new results.”

This research was published in the journal

Full title: Observations of the seiche that shook the world

DOI: 10.1038/s41467-025-59851-7

ֱ is globally renowned for its pioneering research, outstanding teaching and learning, and commitment to social responsibility. We are a truly international university – ranking in the top 50 in a range of global rankings – with a diverse community of more than 44,000 students, 12,000 staff and 550,000 alumni from 190 countries.  Sign up for our e-news to hear first-hand about our international partnerships and activities across the globe. 

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Tue, 03 Jun 2025 15:13:55 +0100 https://content.presspage.com/uploads/1369/4ed0836c-ba8e-41fb-8fcf-4b5bdc0855e7/500_mountainstoweroverdicksonlakeaglacier-fedbodyofwaterintorresdelpainenationalparkinchile.creditaudreypaynensidc.jpg?10000 https://content.presspage.com/uploads/1369/4ed0836c-ba8e-41fb-8fcf-4b5bdc0855e7/mountainstoweroverdicksonlakeaglacier-fedbodyofwaterintorresdelpainenationalparkinchile.creditaudreypaynensidc.jpg?10000
Future-proofing agriculture: scientists look to biotechnology to improve crop resilience and nutritional value /about/news/future-proofing-agriculture/ /about/news/future-proofing-agriculture/707468A new project, co-led by Dr Joshua James and of the at ֱ, in collaboration with theand , will look at how engineering biology technologies can be developed and used to help feed a growing population while protecting crops against climate change-related catastrophes and pests. The project will focus on potatoes, a staple crop for millions of people.

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, and home to the , we are focused on finding new and more sustainable ways to produce chemicals, materials, and everyday products, by understanding and harnessing nature’s own processes and applying them at industrial scales. Find out more via our .

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Funded by a £8.5M grant from the UK Government’s , the researchers will leverage advances in engineering biology to establish synthetic plant chromosome (synPAC) technologies. These technologies promise to provide powerful new ways of introducing novel traits to plants —such as producing essential nutrients or increased pest resistance—while maintaining the plant’s existing characteristics.

Learning from nature: improving crops for people and the planet

Modern agriculture faces significant challenges, from climate change to soil degradation and food security concerns. However, traditional plant breeding and selection can take decades to introduce beneficial traits, relying on random genetic mixing over multiple generations.

This project will develop synPACs, a novel system for rapidly designing and delivering beneficial traits to plants. Building on natural processes, synPACs enable researchers to rapidly introduce multi-gene traits in a far more precise, controllable, and predictable fashion — offering an innovative alternative to conventional breeding methods.

To achieve this, scientists at ֱ will develop unique new technologies that will allow crop scientists to design and build chromosomes carrying desired traits. synPACs will use to efficiently assemble large segments of plant DNA into synthetic chromosomes, prior to direct transfer to crop plants using highly efficient methods developed at the John Innes Centre, and characterised at the Earlham Institute.

The Earlham Institute will lead on three areas of the project; potato tissue atlas and regulatory element discovery, assembly and testing of a potato regulatory element library through the , and engineering synPAC components and synPAC maintenance.

The first phase of the project will focus on potatoes, a globally important crop, with the goal of developing technology pipelines to fast-track plant engineering. Initial target traits will include enhanced nutritional content and resilience against environmental stressors, as well as improving agricultural sustainability by reducing reliance on chemical inputs while improving crop yields. By enabling plants to efficiently produce valuable compounds, synPACs could also support the development of new, plant-based sources of essential nutrients and bioactive compounds, benefiting both human health and the environment.

Ensuring stability, safety and ethics

The synPAC initiative is committed to working transparently with industry partners, regulators, and the public to ensure responsible development and application of this technology. The research team is focused on delivering benefits for both farmers and consumers, ensuring that crops developed through this platform align with the highest standards of safety, sustainability, and societal acceptance. The synPAC team will work closely with social science teams also funded by ARIA to explore these critical issues.

With a clear roadmap for Phase Two, the synPAC team aims to expand this technology to other staple crops, ultimately ushering in a new age of crops optimised for climate resilience, nutrition, and sustainability.

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Mon, 02 Jun 2025 12:00:00 +0100 https://content.presspage.com/uploads/1369/8d887cb8-0024-45c7-8039-ab23aaf46cc9/500_aria-potato-1920x1080.jpg?10000 https://content.presspage.com/uploads/1369/8d887cb8-0024-45c7-8039-ab23aaf46cc9/aria-potato-1920x1080.jpg?10000
Can brightening clouds cool the planet? Manchester-led project to explore innovative solution to avert climate tipping points /about/news/can-brightening-clouds-cool-the-planet-manchester-led-project-to-explore-innovative-solution-to-avert-climate-tipping-points/ /about/news/can-brightening-clouds-cool-the-planet-manchester-led-project-to-explore-innovative-solution-to-avert-climate-tipping-points/706198As the effects of climate change grow more severe, a team of leading scientists is launching a groundbreaking research project to investigate whether climate cooling solutions such as marine cloud and sky brightening could help prevent the worst impacts of global warming.

Climate scientists agree that the primary focus for reducing global warming and the associated climate change is through rapid decarbonisation to reduce our emissions of greenhouse gases. However, current global pledges for reduction of carbon dioxide emissions mean that soon the planet will exceed the 1.5C above pre-industrial levels that was agreed in the legally binding Conference of Parties (COP21). These issues have led to so-called ‘Climate Intervention’ proposals.

The REFLECT project, led by ֱ in collaboration with the National Centre for Atmospheric Science (NCAS) will explore the feasibility and risks of the intervention, which involves spraying tiny sea salt particles into the atmosphere above the ocean to help reflect sunlight back into space, potentially cooling the planet to reduce the risk of triggering damaging climate tipping points.

REFLECT, which stands for ‘REsponsible innovation Framework for assessing noveL spray tEChnology research To examine local albedo changes from marine brightening and its multi-scale impacts’, will investigate how cloud and sky brightening techniques can be responsibly and effectively tested and assessed, but will stop short of any potential real-world application at scale.

Marine cloud and sky brightening techniques involve spraying fine mists of seawater into the atmosphere above the ocean or coastal environments.

The techniques involve enhancing the natural process of cloud formation and are inspired by the natural effects of sea spray on cloud properties over the ocean. The sea salt aerosol particles act as sites for the formation of cloud droplets when the air becomes humid enough, the more particles present, the more cloud droplets form and the more reflective clouds become. The additional sea salt enhances cloud droplet formation and increases the cloud’s reflectivity, which scatters more sunlight back to space and prevents some solar radiation from reaching the Earth’s surface in that area.

Professor Coe added: “There is very limited understanding of whether such approaches are scientifically sound, so it is essential that we understand whether spraying sea water can be performed effectively and what the effects might be.

“By combining cutting-edge technology, rigorous scientific evaluation, and responsible innovation principles, this research aims to provide crucial insights into the feasibility.”

The REFLECT project brings together scientists and engineers from the Universities of Manchester, Cambridge, Exeter and Leeds, the National Centre for Atmospheric Sciences, along with Archipelago Technologies and the Finnish Meteorological Institute and is funded by the UK’s Advanced Research + Invention Agency (ARIA).

The REFLECT team will focus on three key areas:

  • Technology development – Scientists at Manchester will use lab-based chamber studies to determine the ideal size and rate of formation of sea salt aerosol particles, and engineers at Cambridge and Archipelago will develop advanced spray technologies such as superheated atomisation, electrospraying, and bubble-bursting atomisation. The team will evaluate      these approaches for their efficiency, energy use and effectiveness for operation in real-world marine environments.
  • Outdoor experiments – If indoor testing suggests that sprays suitable for  marine cloud and sky brightening techniques can be produced, the team will look to conduct controlled, small-scale, time-bound experiments, coordinated by Manchester,  to assess how different spray methods perform under natural conditions. These experiments will be subject to an independent and publicly available environmental impact and legal assessment, as well as a co-design process with local communities. Researchers from Manchester and NCAS will closely monitor the impact on cloud formation, local weather patterns, and environmental safety, in compliance with  ARIA’s stringent oversight and governance framework that prioritises transparency, ethics and public engagement.
  • Climate modelling and risk analysis – The team members from Exeter and the Finnish Meteorological Institute will use state-of-the-art climate models to simulate the potential effects that cloud and sky brightening might have on regional and global weather patterns if these techniques were one day used over much larger areas than those probed in the outdoor experiments. This will help predict potential benefits and risks and will be critical in determining whether such interventions could be scaled up safely and effectively.

Alongside the scientific and engineering developments, the project will engage with the public, diverse experts, and stakeholders to address key concerns.

Mark Symes, Programme Director at ARIA, said: "The only long-term solution to climate change is rapid decarbonisation — and that must remain the priority. But regardless of emissions cuts, there is growing concern we may pass tipping points in the Earth’s system. ARIA’s programme is focused on generating fundamental scientific evidence about whether any proposed climate cooling approaches could ever be safe or feasible — or whether they should be ruled out entirely.

"This research is essential, it is a deliberate step toward informed global decision-making. In some cases, it may show that even small-scale interventions are ineffective — meaning larger-scale experiments are unnecessary. 

"A small proportion of the projects we are funding involve proposals for small-scale, controlled outdoor experiments. If these go ahead, they will be time-limited, fully reversible, and smaller in magnitude than common natural events. No toxic materials, no large-scale trials, and no deployment. All experiments will undergo legal and environmental assessments, published in advance, with transparency and community engagement built in from the start.

"Our goal is to build knowledge — and help shape global standards for how this science is done responsibly. The programme will not fund, and does not support, the deployment of any climate cooling approaches."

As the climate crisis intensifies, the team hope that projects like REFLECT will help ensure that any potential climate interventions are informed by solid science, ethical considerations, and public transparency.

Nb: This funding is subject to final contract negotiation.   

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Fri, 16 May 2025 12:14:13 +0100 https://content.presspage.com/uploads/1369/7f6706ae-725b-4325-be8d-c9c1405155a5/500_pexels-enrique72-11889506.jpg?10000 https://content.presspage.com/uploads/1369/7f6706ae-725b-4325-be8d-c9c1405155a5/pexels-enrique72-11889506.jpg?10000
New research to reveal hidden microbial impact on CO2 storage /about/news/new-research-to-reveal-hidden-microbial-impact-on-co2-storage/ /about/news/new-research-to-reveal-hidden-microbial-impact-on-co2-storage/706018A new research project led by scientists at ֱ in collaboration with global energy company Equinor ASA will unlock crucial insights into how microbes in deep underground storage sites could impact the success of carbon capture and storage (CCS).

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A new research project led by scientists at ֱ in collaboration with global energy company Equinor ASA will unlock crucial insights into how microbes in deep underground storage sites could impact the success of carbon capture and storage (CCS).

As the UK strives to reach Net Zero emissions by 2050, secure and permanent geological storage of CO₂ is essential to avoid the worst-case consequences of climate change.

Storage in deep geological formations such as depleted oil and gas reservoirs and saline aquifers offers a promising solution. However, these underground environments host diverse microbial ecosystems, and their response to CO₂ injection remains poorly understood.

This knowledge gap poses a potential risk to long-term CO₂ storage integrity. While some microbial responses may be beneficial and enhance mineralogical or biological CO₂ sequestration, others could be unfavourable, leading to methane production, corrosion of infrastructure, or loss of injectivity.

The new flagship project with ֱ and Equinor - global leaders in geological CO₂ storage - will investigate how subsurface microbial communities respond to CO₂ injection and storage, highlighting both the potential risks and opportunities posed by these microbes.

Principal Investigator, Prof Sophie Nixon, BBSRC David Phillips and Dame Kathleen Ollerenshaw Fellow at ֱ, said: "Over the past 20 years, scientists have tested storing CO₂ underground in real-world conditions, but we still know little about how this affects native and introduced microbes living deep below the surface.

"Previous studies have shown that injecting CO₂ underground actively changes microbial communities. In some cases, microbes initially decline but later recover, potentially influencing the fate of injected CO₂ in geological storage scenarios. However, these studies predate the advent of large-scale metagenomic sequencing approaches. A deep understanding of who is there, what they can do and how they respond to CO₂ storage is crucial for ensuring the long-term success of carbon capture and storage."

The two-year project will collect samples from saline aquifer and oil producing sites to study how microbes living deep underground respond to high concentrations of CO2 by combining geochemistry, gas isotope analysis, metagenomic and bioinformatic approaches.

Project Co-Investigator, Dr Rebecca Tyne, a Dame Kathleen Ollerenshaw Fellow at ֱ, said: “To date, Carbon Capture and Storage research has focused on the physiochemical behaviour of CO2, yet there has been little consideration of the subsurface microbial impact on CO2 storage. However, the impact of microbial processes can be significant. For instance, my research has shown that methanogenesis may modify the fluid composition and the fluid dynamics within the storage reservoir.”

Currently, the North Sea Transition Authority requires all carbon capture and storage sites to have a comprehensive ‘Measurement, Monitoring and Verification’ strategy, but microbial monitoring is not yet included in these frameworks. The project’s findings will be shared with industry stakeholders and published in leading scientific journals, helping to close this critical gap and shape future operational activities.

Project Lead, Leanne Walker, Research Associate in Subsurface Microbiology at ֱ, said: "This project will help us understand the underground microbial communities affected by CO₂ storage—how they respond, the potential risks and benefits, and the indicators that reveal these changes.

"Our findings will provide vital insights for assessing microbiological risks at both planned and active CCS sites, ensuring safer and more effective long-term CO₂ storage”.

Biotechnology is enabling us to find new and more sustainable ways to produce chemicals, materials, and everyday products, by understanding and harnessing nature’s own processes and applying them at industrial scales. Supported by the Manchester Institute of Biotechnology, our 400+ experts are innovating solutions in environmental sustainability, health and sustainable manufacturing. Find out more about our biotechnology research.  

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Thu, 15 May 2025 13:40:16 +0100 https://content.presspage.com/uploads/1369/b5ad7ad2-ad88-4c84-b149-7c8050779455/500_renewable-energy-7143345-1280.jpg?10000 https://content.presspage.com/uploads/1369/b5ad7ad2-ad88-4c84-b149-7c8050779455/renewable-energy-7143345-1280.jpg?10000
ֱ Advances Zero-Emission Hydrogen Aviation /about/news/the-university-of-manchester-advances-zero-emission-hydrogen-aviation/ /about/news/the-university-of-manchester-advances-zero-emission-hydrogen-aviation/705110ֱ is part of a UK-led consortium propelling the aviation industry towards a zero-emissions future with cutting-edge hydrogen fuel cell technologies, in line with the UK’s low-carbon energy transition.

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ֱ is part of a UK-led consortium propelling the aviation industry towards a zero-emissions future with cutting-edge hydrogen fuel cell technologies, in line with the UK’s low-carbon energy transition.

Led by GKN Aerospace, the consortium includes experts from ֱ, the University of Birmingham, Newcastle University, and the University of Nottingham, working in collaboration with industry partners Parker-Meggitt, Intelligent Energy, Aeristech, and the Aerospace Technology Institute. Together, we’re addressing the technical challenges of delivering hydrogen-fuelled regional and sub-regional aircraft, which emit only water vapour.

Aviation is a major contributor to climate change, responsible for around 7% of the UK’s greenhouse gas emissions. In 2022 alone, the UK aviation sector emitted the equivalent of 30 million tonnes of carbon dioxide (CO₂). Transitioning to hydrogen-powered flight, which emits zero CO₂ and NOx, is seen as critical to reducing the sector’s environmental footprint.

The collaborative research is being delivered through three projects:

  • H2GEAR – A £54 million programme developing hydrogen-fuelled, cryogenically cooled, all-electric aircraft for short-haul flights.
  • HyFIVE – Backed by £40 million, this project focuses on scalable liquid hydrogen fuel system technologies.
  • H2flyGHT – A £44 million initiative to scale hydrogen-powered aircraft technologies to support larger, commercial-scale aircraft.

At the core of these innovations are hydrogen fuel cells that generate electricity from cold, liquid hydrogen without combustion. Unlike rocket engines that burn hydrogen, these systems convert hydrogen’s flow into electric power, offering a quieter, cleaner and more efficient means of propulsion.

A crucial aspect of the H2GEAR programme is being led by ֱ, where Professor Sandy Smith and his team are pioneering the use of cryogenic cooling to increase energy efficiency. Their research leverages the extreme cold of liquid hydrogen (below -250°C) to supercool electrical components (below -200°C), significantly reducing electrical resistance. This results in hyperconducting systems, capable of powering electric propulsion motors with over 99% efficiency. Unlike superconductors, which rely on exotic materials and complex conditions, hyperconducting systems use more conventional conductors to deliver superior performance more rapidly and cost-effectively.

Russ Dunn, Chief Technology Officer at GKN Aerospace, said: “Hydrogen-powered aircraft offer a clear route to keep the world connected, with dramatically cleaner skies. The UK is at the forefront of this technology, and the H2GEAR project is an example of industry, academia and Government collaboration at its best.”

Launched in 2020 with support from the Aerospace Technology Institute and industrial partners, the H2GEAR programme is set to conclude in 2025. A small-scale demonstrator of the hydrogen-powered propulsion motor is currently undergoing testing at ֱ, with full integration of hyperconducting electric systems projected for as early as 2035.

The UK Hydrogen Alliance estimates that hydrogen-powered aviation could contribute over £30 billion annually to the UK aerospace sector. With this collaborative research leading the way, the UK is set to become a global leader in sustainable aviation innovation.

Our research is at the forefront of the energy transition. Guided by our innovative spirit and interdisciplinary outlook, we work to mitigate climate change while transforming our energy system, to enable a just and prosperous future for all. Find out more about our energy research. 

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Thu, 08 May 2025 15:03:00 +0100 https://content.presspage.com/uploads/1369/2ec39ebd-4e98-4146-ac7d-dea53e047bdf/500_image1.png?10000 https://content.presspage.com/uploads/1369/2ec39ebd-4e98-4146-ac7d-dea53e047bdf/image1.png?10000
Manchester scientists develop new light-powered enzymes to make chemistry cleaner and greener /about/news/new-light-powered-enzymes/ /about/news/new-light-powered-enzymes/704767Researchers at the Manchester Institute of Biotechnology (MIB) have demonstrated how genetically engineered enzymes can harness visible light to drive highly selective chemical reactions.This breakthrough could lead to cleaner, more efficient ways of making medicines and other important chemicals, all while reducing the need for harsh chemicals and harmful ultraviolet (UV) light. The discovery, which represents a major step forward in the field of photocatalysis - using light to drive chemical reactions - shows how biology and chemistry can work hand-in-hand to unlock new possibilities for safer, greener manufacturing.

Swapping harmful UV for everyday visible light

Many light-driven chemical processes rely on UV light and chemical helpers called ‘sensitisers’, which absorb the light and transfer the energy to the other molecules to drive the reaction. Previous research from the MIB had selectively introduced UV sensitisers into proteins that resulted in photoenzymes that were more efficient, selective and versatile than traditional small molecule sensitisers. However, these UV-driven photoenzymes have downsides: they suffer from low photochemical efficiencies, can damage delicate molecules, and often produce unwanted by-products, therefore limiting the scope of possible reactions.

To address these issues, Dr Rebecca Crawshaw and Dr Ross Smithson, part of the Green Group, led by , engineered enzymes that contain a different type of light-absorbing molecule called thioxanthone. Unlike older sensitisers, thioxanthone works with visible light, making the system not only more efficient but also more environmentally friendly and compatible with industrial lighting conditions.

Improved efficiency from a nature-inspired design

By embedding these thioxanthone sensitisers directly into enzymes, the scientists have created new ‘photoenzymes’ that can perform light-powered reactions with remarkable speed and accuracy.

One of these enzymes, named VEnT1.3, was able to produce its target chemical with significantly improved efficiency—completing over 1,300 reaction cycles and doing so with precise control over the arrangement of atoms. This level of control is especially important when making pharmaceuticals, where the 3D shape of a molecule can mean the difference between a life-saving drug and an ineffective or harmful substance.

The new photoenzymes also open new pathways for manufacturing as they can achieve chemical reactions that would be difficult, or even impossible, to do using traditional chemical methods. For example, the team developed a second enzyme, called SpEnT1.3, which can build complex ring-shaped molecules known as spirocyclic β-lactams. These are important building blocks for medicines and other high-value chemicals.

Additionally, the photoenzymes can also suppress undesired decomposition pathways that commonly plague small-molecule photocatalysis. These findings highlight the unique capability of engineered enzymes to govern the fate of reactive intermediates with a level of control that remains out of reach for conventional catalysts.

A greener future for chemical manufacturing

The success of this genetic encoding approach underscores the broader potential of using engineered enzymes as a flexible platform for visible-light photocatalysis. By expanding the genetic code to incorporate novel sensitisers like thioxanthone, researchers can fine-tune photoenzyme scaffolds for a wide array of reactions—alleviating many of the limitations imposed by more traditional photocatalysts.

The research also highlights the power of combining cutting-edge science from different fields—genetic engineering, chemistry, and biology—to solve practical problems. By expanding the genetic ‘toolkit’ that scientists use to build enzymes, the team can design these biological catalysts to do exactly what’s needed, in the right place, at the right time.

Such advances could ultimately facilitate the design of enzyme systems capable of performing complex photochemical transformations with unmatched precision and efficiency—benefiting sectors ranging from pharmaceuticals and agrochemicals to materials science and beyond.

Biotechnology is enabling us to find new and more sustainable ways to produce chemicals, materials, and everyday products, by understanding and harnessing nature’s own processes and applying them at industrial scales. Supported by the Manchester Institute of Biotechnology, our 400+ experts are innovating solutions in environmental sustainability, health and sustainable manufacturing. Find out more about our biotechnology research.  

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Wed, 07 May 2025 08:00:00 +0100 https://content.presspage.com/uploads/1369/df893998-1367-4a30-8446-5713e399b5c7/500_mib-0920.jpg?10000 https://content.presspage.com/uploads/1369/df893998-1367-4a30-8446-5713e399b5c7/mib-0920.jpg?10000
Long-term field experiment shows combined approach can maximise the benefits of grassland restoration /about/news/long-term-field-experiment-shows-combined-approach-can-maximise-the-benefits-of-grassland-restoration/ /about/news/long-term-field-experiment-shows-combined-approach-can-maximise-the-benefits-of-grassland-restoration/704737Results from a long-term field experiment shed new light on how grasslands can be restored for nature, the environment, and for farmers.

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Results from a long-term field experiment shed new light on how grasslands can be restored for nature, the environment, and for farmers.

From richer biodiversity and benefits for pollinators, to carbon storage in soils, while balancing hay yields for grazing livestock, the study published in by researchers at ֱ and Lancaster University, in collaboration with the Universities of Yale and Bergen, shows that using combinations of different restoration techniques can markedly enhance the restoration of grasslands.

Given many current grassland recovery projects typically only use one type of technique, or ‘intervention’, in attempts to deliver ecological benefits, the scientists behind the study hope their findings can help boost grassland restoration initiatives across the country and elsewhere,

Grasslands cover nearly 40% of the Earth’s land surface and serve as important global reservoirs of biodiversity. They also provide a host of other benefits to people, termed ecosystem services, including food production, water supply, carbon storage, soil nutrient cycling, and tourism. Yet these critical ecosystems are increasingly being degraded, especially by overgrazing, heavy use of fertilisers, and climate change. This is undermining their ability to support biodiversity and deliver other benefits, such as carbon storage and nutrient retention.

The team of scientists show that using single restoration interventions often leads to trade-offs among key grassland ecosystem services – for example the addition of low amounts of fertiliser boosted hay yields for livestock, but suppressed plant diversity. Also, while the addition of a seed mix alone increased plant diversity and pollination, bringing benefits for nature conservation, it did not benefit hay yield or soil carbon storage. They show that using a combination of different techniques delivers better, more balanced ecological benefits than relying on one single type of intervention.

The combined approach to grassland restoration boosted plant diversity, soil health, carbon storage, pollination, flower abundance, and forage production simultaneously, offering a clear path forward for sustainable land management.

The work was based on a long-term grassland restoration experiment set up in 1989 at Colt Park Meadows, in the Yorkshire Dales, northern England. The experiment included a range of commonly used grassland restoration interventions, including the addition of farmyard manure, low-level inorganic fertiliser, a diverse seed mix, and a nitrogen-fixing red clover, which were tested individually and in all possible combinations. Over several years, between 2011 and 2014, the team measured 26 critical ecosystem functions related to hay yield, soil carbon storage, soil nutrient cycling, soil structure, water quality, pollinator visitation, and plant diversity.

Dr Shangshi Liu, the lead author of the paper from ֱ and now based at Yale, said: “Single solutions are rarely enough—we need landscapes that work on many levels: for climate, for people, and for nature. By layering complementary actions that target different components of the ecosystem, we can restore a broader suite of ecosystem functions—balancing trade-offs and minimising unintended consequences.”

Professor Richard Bardgett, who initiated the study at ֱ and recently moved to Lancaster, added: “These findings evidence the potential of combining interventions to boost the restoration of degraded grasslands. By combining interventions, such as adding more diverse plant seeds, small amounts of fertiliser, manure and red clover, we show that it is possible to balance hay yields for livestock as well as boosting biodiversity, carbon storage, and wild flower abundance, although each combination will need to be tailored for specific sites. These findings represent a shift from conventional approaches that typically rely on single management interventions.

“In doing so, they offer a blueprint for land managers and policymakers seeking to deliver multiple benefits from grassland restoration, which aligns the UN Decade on Ecosystem Restoration (2021–2030) that calls for integrated solutions to ecological degradation.”

The researchers also call for further experimentation across different climates and grassland types, alongside policy frameworks that incentivise grassland restoration. Programmes that currently support single interventions for grassland restoration could be restructured to favour integrated approaches that deliver broader ecological returns of benefit to a wider range of land users.

Ben Sykes, Director of the Ecological Continuity Trust (ECT), who work to secure long-term experiments such as Colt Park, said: “The Colt Park Meadows long-term grassland restoration experiment, running since 1989, is one of many decades-long ecological field experiments (LTEs) across the UK that are linked via the ECT’s national register of experimental sites. These latest results from the Colt Park LTE help demonstrate the irreplaceable value of LTEs in providing the real-world scientific evidence needed to promote conservation, biodiversity restoration and future effective and sustainable land management.”

The study was funded by the UK Department of Environment, Food and Rural Affairs and Natural Environment Research Council (NERC), and benefits from long term support from Natural England.

The study’s findings are detailed in the paper ‘Multiple targeted grassland restoration interventions enhance ecosystem service multifunctionality’ which has been published by .

DOI: 10.1038/s41467-025-59157-8

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Tue, 06 May 2025 09:00:24 +0100 https://content.presspage.com/uploads/1369/fe7b321b-27dc-46f8-8d86-f356fb2822a6/500_coltparkstudysite.creditprofessorrichardbardgett.jpg?10000 https://content.presspage.com/uploads/1369/fe7b321b-27dc-46f8-8d86-f356fb2822a6/coltparkstudysite.creditprofessorrichardbardgett.jpg?10000
New mass-spectrometry technique boosts enzyme screening speed by up to 1000 times /about/news/new-mass-spectrometry-technique-boosts-enzyme-screening-speed-by-up-to-1000-times/ /about/news/new-mass-spectrometry-technique-boosts-enzyme-screening-speed-by-up-to-1000-times/703739Scientists have developed  a new technique to screen engineered enzyme reactions, which could lead to faster and more efficient creation of medicines and sustainable chemicals.

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Scientists have developed  a new technique to screen engineered enzyme reactions, which could lead to faster and more efficient creation of medicines and sustainable chemicals.

Enzymes are proteins that catalyse chemical reactions, turning one substance into another. In labs, scientists engineer these enzymes to perform specific tasks like the sustainable creation of medicines, and materials. These biocatalysts have many environmental benefits as they often produce higher product quality, lower manufacturing cost, and less waste and reduced energy consumption. But to find ‘the one’, scientists must test hundreds of variants for their effectiveness, which is a slow, expensive, and resource-intensive process.

Research conducted by ֱ in collaboration with AstraZeneca is changing this. The team developed a method for a technique that can test enzyme activity up to 1,000 times faster than traditional methods. The new method, developed over the last eight years and detailed today in the journal  is called DiBT-MS (Direct Analysis of Biotransformations with Mass Spectrometry).

It builds on an existing technology called DESI-MS (Desorption Electrospray Ionization Mass Spectrometry), a powerful tool that allows scientists to analyse complex biological samples without the need for extensive sample preparation. 

By making small adaptations to the technology, the scientists designed a protocol to directly analyse enzyme-triggered chemical reactions, known as biotransformations, in just minutes. The new method can process 96 samples in just two hours—tasks that would previously take days using older techniques.

It has also been optimised to allow the researchers to reuse sample slides multiple times improving testing efficiency and decreasing the use of solvents and plasticware.

The team has already successfully applied this technique to a range of enzyme-driven reactions, including those enzymes particularly valuable in the development of therapeutics.

Looking ahead, ֱ will continue to explore ways to boost partnerships between laboratories and tackle other challenges that often hinder collaboration, such as geographical barriers and limited funding.

This research was partly funded by a UKRI Prosperity Partnership grant in collaboration with AstraZeneca.

Journal: Nature Protocols

Full title: Direct analysis of biotransformations with mass spectrometry—DiBT-MS

DOI: 10.1038/s41596-025-01161-9

Link:

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Mon, 28 Apr 2025 10:21:00 +0100 https://content.presspage.com/uploads/1369/c1dbdf9b-180a-456d-afaf-80f05bec6de1/500_mib-1138.jpg?10000 https://content.presspage.com/uploads/1369/c1dbdf9b-180a-456d-afaf-80f05bec6de1/mib-1138.jpg?10000
Breathing easy: the future of healthcare ventilation /about/news/the-future-of-healthcare-ventilation/ /about/news/the-future-of-healthcare-ventilation/694361Following on from his , Dr Amir Keshmiri is now taking his research into a clinical setting. Working with industrial partner, Howorth Air Technology (HAT), Amir and the project team will implement their new ventilation metrics in HAT’s ultra clean ventilation systems to improve patient health and wellbeing.

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In the wake of the COVID-19 pandemic, clean air in healthcare settings – specifically hospices where some of society’s most vulnerable patients convalesce – has never been more important. While current ventilation systems effectively help manage indoor CO2 levels, they often do little to mitigate cross-infection between patients and healthcare workers. and , from ֱ, are working with Howorth Air Technology Limited (HAT) to implement his advanced airflow modelling metrics into HAT’s ultra clean ventilation systems to reduce cross-infection risk and improve ventilation efficiency.

Transforming traditional ventilation

Current ventilation systems rely predominantly on fresh air intake, mechanical system design, and air velocity to mitigate infection risk (IR). In response to the COVID-19 pandemic, trade bodies around the world issued ventilation guidelines based on these key metrics to help prevent the disease spreading in indoor settings, however this approach is overly simplistic and doesn’t take into account the relationship between viral load, exposure time and individual susceptibility.

The researchers actively looked to address this gap and so, using advanced computational simulations, took a holistic approach, analysing the spatial-temporal relationship of airborne pathogens with a view to incorporating this into wider healthcare settings.

Following an effective pilot in a hospice in the UK, Amir successfully secured funding through the Engineering and Physical Sciences Research Council (EPSRC) which will allow him to take his research to the next stage and work with an industrial partner to design a new generation of ventilation system.

For patients, healthcare professionals, and the planet

This project aims to allow hospitals to fine-tune their ventilation systems and minimise infection risks, keeping both patients and healthcare professionals safer while also improving energy efficiency. Healthcare-associated infections remain a persistent challenge, costing lives and placing immense strain on the NHS. If hospitals can harness these advanced ventilation insights it could result in fewer infections, shorter hospital stays, and lower costs for an already overstretched healthcare service.

From an environmental standpoint, the benefits are just as compelling. The NHS has committed to becoming the world’s first net-zero health service, but traditional ventilation systems are notoriously energy-intensive. By improving the way air is circulated and filtered, this project could help reduce energy consumption without compromising on safety. In an age where sustainability is no longer a choice but a necessity, this shift towards high-performance, energy-efficient ventilation couldn’t come at a better time.

Finally, these innovations could help redefine ventilation guidelines at a national level, influencing NHS standards and setting new benchmarks for the global healthcare industry.

The road ahead

Of course, no innovation is without its challenges. Integrating these new ventilation effectiveness metrics into NHS standards will take time, and convincing hospitals to move beyond traditional air velocity measures won’t happen overnight. But the case for change is undeniable.

The UK government has already acknowledged the crucial role ventilation plays in reducing airborne disease transmission. With new guidelines on infection control and increasing pressure to improve energy efficiency, the timing couldn’t be better for a shift in hospital ventilation strategies. 

In a world where healthcare is under more pressure than ever, this initiative is a reminder that sometimes, the biggest breakthroughs come not from high-tech drugs or cutting-edge surgical techniques, but from something as fundamental as the air we breathe. With this partnership poised to redefine hospital ventilation, the future of healthcare is looking clearer—and cleaner—than ever.

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Thu, 24 Apr 2025 16:57:13 +0100 https://content.presspage.com/uploads/1369/0eaf562a-74a2-400c-acfc-c8ce889182f6/500_streamlinespicture1920x1080.jpg?10000 https://content.presspage.com/uploads/1369/0eaf562a-74a2-400c-acfc-c8ce889182f6/streamlinespicture1920x1080.jpg?10000
Manchester physicist among global researchers honoured with prestigious Breakthrough Prize /about/news/manchester-physicist-among-global-researchers-honoured-with-prestigious-breakthrough-prize/ /about/news/manchester-physicist-among-global-researchers-honoured-with-prestigious-breakthrough-prize/697910Physicists from ֱ are among global researchers part of CERN’s Large Hadron Collider (LHC) collaborations, who have been honoured with the 2025 .

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Physicists from ֱ are among global researchers part of CERN’s Large Hadron Collider (LHC) collaborations, who have been honoured with the 2025 .

The Breakthrough Prize – popularly known as the “Oscars of Science” – honours scientists driving remarkable discoveries. 

CERN’s four major LHC experiment collaborations — , , , and  — have been recognised for testing the modern theory of particle physics – the Standard Model – and other theories describing physics that might lie beyond it to high precision.

In particular, the team have been awarded for discoveries made during the LHC Run-2 data up to July 2024, including detailed measurements of Higgs boson properties, the discovery of new particles, matter-antimatter asymmetry and the exploration of nature at the shortest distances and most extreme conditions.

ֱ researchers are involved in two of the four projects, ATLAS and LHCb. ATLAS is designed to record the high-energy particle collisions of the LHC to investigate the fundamental building blocks of matter and the forces governing our universe in order to better understand building blocks of life, while LHCb focuses on investigating the slight differences between matter and antimatter.

, Head of Physics and Astronomy at ֱ and former leader of the LHCb experiment explained that for his experiment “the department constructed a silicon pixel based ‘camera’ for the new version of the experiment that takes images 40 million times per second. Members played significant roles in the discovery of new matter antimatter differences and the discovery of new particles”.

The four LHC experiment collaborations involve thousands of researchers from over 70 countries. The $3M award was collected at a ceremony in LA by Parkes’ successor as leader of the experiment along with the leaders of the other three experiments.

Following consultation with the experiments’ management teams, the Breakthrough Prize Foundation will donate the $3 million Prize to the . The Prize money will be used to offer grants for doctoral students from the collaborations’ member institutes to spend research time at CERN, giving them experience in working at the forefront of science and new expertise to bring back to their home countries and regions.

Going forward, the LHC experiments will continue to push the boundaries of knowledge of fundamental physics to unprecedented limits. The upcoming upgrade of the Large Hadron Collider, the High-Luminosity LHC, which many of ֱ’s physicists and engineers are involved in, aims to ramp up the performance of the LHC, starting in 2030, in order to increase the potential for discoveries.

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Wed, 23 Apr 2025 10:17:45 +0100 https://content.presspage.com/uploads/1369/e2f2ee8d-fecf-47a1-b6ea-31dfa71e440f/500_btp-2025-0.jpg?10000 https://content.presspage.com/uploads/1369/e2f2ee8d-fecf-47a1-b6ea-31dfa71e440f/btp-2025-0.jpg?10000
ֱ and Amentum expand strategic partnership on world-changing technologies /about/news/the-university-of-manchester-and-amentum-expand-strategic-partnership-on-world-changing-technologies/ /about/news/the-university-of-manchester-and-amentum-expand-strategic-partnership-on-world-changing-technologies/694433ֱ has expanded its collaboration with Amentum, a global leader in advanced engineering and innovative technology solutions, to drive advances in materials science, robotics, digitalisation, energy and social impact. 

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ֱ has expanded its collaboration with , a global leader in advanced engineering and innovative technology solutions, to drive advances in materials science, robotics, digitalisation, energy and social impact. 

Andy White, Senior Vice President of Amentum Energy & Environment International, said: “Our relationship with the University is about advancing the future together by combining the power of academic research and industrial know-how.

“By working together, Amentum and the University have had great success in delivering impressive solutions for customers, creating opportunities for our people, and supporting research and development work at both organisations’ laboratories.

“We have now signed a new memorandum of understanding for the next phase of our collaboration, which will see us delivering ground-breaking research and developing new technologies with the potential to change the world and applying them in the industries where Amentum operates.”

For more than a decade, Amentum has collaborated with the University’s on structural integrity, corrosion, robotics and chemistry. This work has helped ensure the safe operation and life extension of the UK’s nuclear power stations and has also enhanced a scientific and technical offering which underpins Amentum’s leading role in key growth areas such as the design and development of small modular and advanced reactors.

More recently, Amentum and the UK government’s Engineering and Physical Sciences Research Council have funded the Centre for Robotic Autonomy in Demanding and Long-lasting Environments with the University to develop advanced robotics for hazardous or hard to access environments and to research the ethical and regulatory implications for society from the proliferation of autonomous systems.

, Vice-Dean for Research and Innovation in the Faculty of Science and Engineering, ֱ, said: “Our University has a proud legacy of research that transforms industries and improves lives – from initiating the computer revolution to isolating graphene. But it's what comes next that will define us. Together with Amentum, we share a bold ambition: to deliver research that is not only world-leading but world-changing.”

Dr Louise Bates, Director of Business Engagement and Knowledge Exchange, ֱ added: “This partnership presents an exciting chance to push boundaries, redefine knowledge and accelerate the journey from discovery to real-world impact. By uniting our community's pioneering research with Amentum’s expertise, we can deliver positive change for society and the environment by tackling some of the greatest challenges facing the industries Amentum serves.”

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Thu, 17 Apr 2025 09:32:49 +0100 https://content.presspage.com/uploads/1369/9cdb7c92-00af-41ce-9435-f5b1dcc059d1/500_uomampamentumimage1-councilchambers.jpeg?10000 https://content.presspage.com/uploads/1369/9cdb7c92-00af-41ce-9435-f5b1dcc059d1/uomampamentumimage1-councilchambers.jpeg?10000
Scientists develop new method to measure and predict hydrogen bond strength in confined water /about/news/scientists-develop-new-method-to-measure-and-predict-hydrogen-bond-strength-in-confined-water/ /about/news/scientists-develop-new-method-to-measure-and-predict-hydrogen-bond-strength-in-confined-water/694115A breakthrough by researchers at ֱ sheds light on one of nature’s most elusive forces, with wide-reaching implications for medicine, energy, climate modelling and more.

Researchers at ֱ have developed a ground-breaking method to precisely measure the strength of hydrogen bonds in confined water systems, an advance that could transform our understanding of water’s role in biology, materials science, and technology. The work, published in , introduces a fundamentally new way to think about one of nature’s most important but difficult-to-quantify interactions.

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A breakthrough by researchers at ֱ sheds light on one of nature’s most elusive forces, with wide-reaching implications for medicine, energy, climate modelling and more.

Researchers at ֱ have developed a ground-breaking method to precisely measure the strength of hydrogen bonds in confined water systems, an advance that could transform our understanding of water’s role in biology, materials science, and technology. The work, published in , introduces a fundamentally new way to think about one of nature’s most important but difficult-to-quantify interactions.

Hydrogen bonds are the invisible forces that hold water molecules together, giving water its unique properties, from high boiling point to surface tension, and enabling critical biological functions such as protein folding and DNA structure. Yet despite their significance, quantifying hydrogen bonds in complex or confined environments has long been a challenge.

“For decades, scientists have struggled to measure hydrogen bond strength with precision,” said , who led the study with and Dr Ziwei Wang. “Our approach reframes hydrogen bonds as electrostatic interactions between dipoles and an electric field, which allows us to calculate their strength directly from spectroscopic data.”

Lead author of the paper Dr Ziwei Wang, holding gypsum crystal, in front of the Raman spectrometer.

The team used gypsum (CaSO₄·2H₂O), a naturally occurring mineral that contains two-dimensional layers of crystalline water, as their model system. By applying external electric fields to water molecules trapped between the mineral’s layers, and tracking their vibrational response using high-resolution spectroscopy, the researchers were able to quantify hydrogen bonding with unprecedented accuracy.

“What’s most exciting is the predictive power of this technique,” said Dr Yang. “With a simple spectroscopic measurement, we can predict how water behaves in confined environments that were previously difficult to probe, something that normally requires complex simulations or remains entirely inaccessible.”

The implications are broad and compelling. In water purification, this method could help engineers fine-tune membrane materials to optimise hydrogen bonding, improving water flow and selectivity while reducing energy costs. In drug development, it offers a way to predict how water binds to molecules and their targets, potentially accelerating the design of more soluble and effective drugs. It could enhance climate models by enabling more accurate simulations of water’s phase transitions in clouds and the atmosphere. In energy storage, the discovery lays the foundation for “hydrogen bond heterostructures”, engineered materials with tailored hydrogen bonding that could dramatically boost battery performance. And in biomedicine, the findings could help create implantable sensors with better compatibility and longer lifespans by precisely controlling water-surface interactions.

“Our work provides a framework to understand and manipulate hydrogen bonding in ways that weren’t possible before,” said Dr Wang, first author of the paper. “It opens the door to designing new materials and technologies, from better catalysts to smarter membranes, based on the hidden physics of water.”

This research was published in the journal Nature Communications.

Full title: Quantifying hydrogen bonding using electrically tunable nanoconfined water

DOI: 

The research was supported by the European Research Council and UK Research and Innovation (UKRI).

The is a world-leading graphene and 2D material centre, focussed on fundamental research. Based at ֱ, where graphene was first isolated in 2004 by Professors Sir Andre Geim and Sir Kostya Novoselov, it is home to leaders in their field – a community of research specialists delivering transformative discovery. This expertise is matched by £13m leading-edge facilities, such as the largest class 5 and 6 cleanrooms in global academia, which gives the NGI the capabilities to advance underpinning industrial applications in key areas including: composites, functional membranes, energy, membranes for green hydrogen, ultra-high vacuum 2D materials, nanomedicine, 2D based printed electronics, and characterisation.

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Tue, 15 Apr 2025 11:11:53 +0100 https://content.presspage.com/uploads/1369/0a462a1a-2fc1-49e8-8ea1-043a6ad411bb/500_bannerimage-zw.png?10000 https://content.presspage.com/uploads/1369/0a462a1a-2fc1-49e8-8ea1-043a6ad411bb/bannerimage-zw.png?10000
ֱ to collaborate with leading innovator in AI-driven automation and robotics /about/news/the-university-of-manchester-to-collaborate-with-leading-innovator-in-ai-driven-automation-and-robotics/ /about/news/the-university-of-manchester-to-collaborate-with-leading-innovator-in-ai-driven-automation-and-robotics/693455ֱ is to collaborate with leading innovator in AI-driven automation and robotics, InGen Dynamics, to create a dynamic ecosystem where academia and industry work hand-in-hand to develop AI-powered solutions that redefine the future of automation and robotics.  

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ֱ is to collaborate with leading innovator in AI-driven automation and robotics, InGen Dynamics, to create a dynamic ecosystem where academia and industry work hand-in-hand to develop AI-powered solutions that redefine the future of automation and robotics.  

The University and the Santa Clara-based company have signed a Memorandum of Understanding (MoU), marking a strategic partnership aimed at leveraging the strengths of both organisations to drive advancements in AI applications across multiple sectors, including healthcare, social care, education, and sustainability. 

This collaboration will provide a foundation for joint research projects, academic exchange programs, and curriculum development initiatives that will shape the future of AI-driven solutions.  

Under the terms of the MoU, the partnership will focus on key initiatives, including:  

Research and Development in AI, Robotics, and Automation – Exploring applications of AI in healthcare, education, and sustainability, including the development of AI-powered robotic solutions such as Fari for elderly care and Senpai for special needs education.   

AI for All Initiative – Facilitating upskilling and workforce development programs in AI and robotics for healthcare, social care, and education professionals.  

Joint Degree Programs and Curriculum Development – Establishing specialized programs in AI, robotics, and automation, incorporating theoretical and practical components with hands-on experience using InGen Dynamics’ technologies, including Fari, Senpai, and Origami AI.  

Social Care Testbed Collaboration – Deploying and evaluating AI-driven robotics solutions in real-world environments to improve care delivery and assess the impact of AI in social care settings.  

AI Ethics and Responsible AI Initiatives – Promoting transparency, accountability, and ethical AI development through collaborative research and policy discussions.  

Global Exchange Programs – Enabling international knowledge-sharing by connecting students and researchers from the University of Manchester with InGen Dynamics’ Futurenauts initiative in India and beyond.  

The collaboration will be overseen by a Steering Committee co-chaired by Professor Andrew Weightman, Professor of Medical Mechatronics the Department of Mechanical and Aerospace Engineering and Arshad Hisham, Founder & CEO of InGen Dynamics. The committee will meet biannually to define strategic roadmaps and identify new areas of mutual interest.  

Mr Hisham, said: “This partnership with ֱ is a significant step toward advancing AI and robotics research that has real-world impact.

“By combining our industry expertise with the academic excellence of Manchester, we aim to accelerate innovation and create transformative AI solutions for global challenges.”  

Professor Weightman added: “We are excited to collaborate with InGen Dynamics to drive forward research and education in AI and automation.

“This MoU will enable us to integrate cutting-edge technology into our programs while fostering innovation that benefits society.”  

 ֱ is globally renowned for its pioneering research, outstanding teaching and learning, and commitment to social responsibility. We are a truly international university – ranking in the top 50 in a range of global rankings – with a diverse community of more than 44,000 students, 12,000 staff and 550,000 alumni from 190 countries.  Sign up for our e-news to hear first-hand about our international partnerships and activities across the globe. 

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Thu, 10 Apr 2025 09:00:00 +0100 https://content.presspage.com/uploads/1369/495f20be-0f98-446f-b477-a4199daaeac6/500_ai.jpg?10000 https://content.presspage.com/uploads/1369/495f20be-0f98-446f-b477-a4199daaeac6/ai.jpg?10000
Manchester scientists contribute to breakthrough in the matter–antimatter puzzle /about/news/manchester-scientists-contribute-to-breakthrough-in-the-matterantimatter-puzzle/ /about/news/manchester-scientists-contribute-to-breakthrough-in-the-matterantimatter-puzzle/693464Physicists have made a landmark discovery, uncovering the first clear evidence that matter particles, known as baryons, behave differently from their antimatter counterparts.

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Physicists have made a landmark discovery, uncovering the first clear evidence that matter particles, known as baryons, behave differently from their antimatter counterparts.

The finding, from CERN's LHCb experiment, which includes scientists at ֱ, provides new understanding of the ‘standard Model’ of particle physics and a new piece in the puzzle to explain how and why matter ended up dominating over antimatter after the big Bang to form the Universe we see today.

The finding was presented at the Rencontres de Moriond conference in La Thuile, Italy, on 24 March and posted on .

Scientists have known since the 1960s that particles have a distinct asymmetry and can behave differently from their antimatter counterparts — a phenomenon called "CP violation." While this effect has been seen before in the break-up of certain particles, known as mesons,  this is the first time it has been definitively observed in particles similar to those of ordinary matter, known as baryons. Baryons, which include protons and neutrons, make up most of the visible matter in the Universe and consist of three quarks.

LHCb spokesperson Vincenzo Vagnoni, said: “The reason why it took longer to observe CP violation in baryons than in mesons is down to the size of the effect and the available data.

“We needed a machine like the Large Hydron Collider (LHC) capable of producing a large enough number of beauty baryons and their antimatter counterparts, and we needed an experiment at that machine capable of pinpointing their decay products. It took over 80 000 baryon decays for us to see matter–antimatter asymmetry with this class of particles for the first time.”

Every particle has an antimatter counterpart with the same mass but an opposite charge. Normally, these pairs should behave like perfect mirror images of each other. However, when particles break down or transform, such as during radioactive decay, this symmetry can be slightly distorted (CP violation). This means that matter and antimatter particles don’t always decay at the same rate. Scientists can detect and measure this tiny difference using advanced detectors and powerful data analysis techniques.

The LHCb collaboration observed CP violation in a particle called the beauty-lambda baryon (Λb), a heavier, short-lived cousin of the proton. They analysed data from millions of particle collisions collected during two runs of the LHC between 2009 and 2018 in search of a certain decay.

The team discovered that the Λb and its antimatter partner do not decay into other particles at exactly the same rate — a difference of about 2.45%. The difference is large enough to exceed the threshold physicists use to confirm an observation of CP violation. Physicists calculate that the odds of such a discrepancy occurring by chance is less than one in three million.

Chris Parkes, Professor of Experimental Particle Physics at ֱ and the former leader of the LHCb collaboration, said: “Without a difference in the behaviour of matter and antimatter there would be not matter in the universe. All the matter and antimatter would have annihilated and the universe today would be made only of light. The LHCb experiment is specifically designed to look at differences between matter and antimatter in the break-up of particles. This is a landmark discovery in these studies, as it is the first time a difference is seen in particles similar to heavy versions of the proton or neutron.”

 The CP violation predicted by the Standard Model is far too small to explain the matter–antimatter asymmetry observed in the Universe. This suggests that there may be additional, unknown sources of CP violation that scientists have yet to discover. Finding these is a key goal of research at the Large Hadron Collider and will remain a focus for future experiments.

 LHCb spokesperson Vincenzo Vagnoni, said: “The more systems in which we observe CP violations and the more precise the measurements are, the more opportunities we have to test the Standard Model and to look for physics beyond it.

“The first ever observation of CP violation in a baryon decay paves the way for further theoretical and experimental investigations of the nature of CP violation, potentially offering new constraints for physics beyond the Standard Model.”

The LHCb Collaboration is continuing its studies with the second generation version of the large experimental apparatus, key elements of which were built in the Physics and Astronomy department at the University of Manchester.

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Mon, 07 Apr 2025 14:40:00 +0100 https://content.presspage.com/uploads/1369/b2f83a70-bc22-4f59-ba02-e83158756690/500_lhcb.creditcern.jpg?10000 https://content.presspage.com/uploads/1369/b2f83a70-bc22-4f59-ba02-e83158756690/lhcb.creditcern.jpg?10000
Even just thinking you’re hungry could change your immune system – new research in mice /about/news/even-just-thinking-youre-hungry-could-change-your-immune-system--new-research-in-mice/ /about/news/even-just-thinking-youre-hungry-could-change-your-immune-system--new-research-in-mice/693137 

Feeling hungry doesn’t just make you reach for a snack – it may also change your immune system.

In a recent study in mice, we found that simply perceiving hunger can change the number of immune cells in the blood, even when the animals hadn’t actually fasted. This shows that even the brain’s interpretation of hunger can shape how the immune system adapts.

Our new research published in challenges the long-standing idea that immunity is shaped primarily by real, physical changes in nutrition, such as changes in blood sugar or nutrient levels. Instead, it shows that perception alone (what the brain “thinks” is happening) can reshape immunity.

We focused on two types of highly specialised brain cells () that sense the body’s energy status and generate the feelings of hunger and fullness in response. AgRP neurons promote hunger when energy is low, while POMC neurons signal fullness after eating.

Using genetic tools, we artificially activated the hunger neurons in mice that had already eaten plenty of food. Activating this small but powerful group of brain cells triggered an intense urge to seek food in the mice. This finding builds on what .

To our surprise, though, this synthetic hunger state also led to a marked drop in specific immune cells in the blood, called monocytes. These cells are part of the immune system’s first line of defence and play a .

Conversely, when we activated the fullness neurons in fasted mice, the monocyte levels returned close to normal, even though the mice hadn’t eaten. These experiments showed us the brain’s perception of being hungry or fed was on its own enough to influence immune cell numbers in the blood.

To understand how this axis between the brain and the immune system works, we then looked at how the brain communicates with the liver. This organ is important in sensing energy levels in the body. has also shown the liver communicates with bone marrow – the soft tissue inside bones where .

We found a direct link between the hunger neurons and the liver via the sympathetic nervous system, which plays a broad role in regulating functions like heart rate, blood flow, and how organs respond to stress and energy demands. When the hunger neurons were turned on, they dialled down nutrient-sensing in the liver by reducing sympathetic activity.

This suggests that the brain can influence how the liver interprets the body’s energy status; essentially convincing it that energy is low, even when actual nutrient levels are normal. This, in turn, led to a drop in a chemical called , which usually helps draw monocytes into the blood. Less CCL2 meant fewer monocytes circulating.

We also saw that hunger signals caused the release of a stress hormone called corticosterone (similar to cortisol in humans). This hormone on its own didn’t have a big effect on immune cell numbers, at least not at the levels that would typically be released while fasting.

Much higher levels of stress hormones are usually needed to affect the immune system directly. But in this case, the modest rise in corticosterone worked more like an amplifier. While it wasn’t enough to trigger immune changes by itself, it was crucial for allowing the response to happen when cooperating with signals coming from the brain.

This further illustrate how the body’s stress system and immune changes are scalable and how they adjust depending on the nature and intensity of the stressful event.

Why might this happen?

Why would the brain do this? Although we haven’t formally tested this, we think one possibility is that this complex, multi-organ communication system evolved to help the body anticipate and respond to potential shortages. By fine-tuning energy use and immune readiness based on perceived needs, the brain would be able to coordinate an efficient whole-body response before a real crisis begins.

If the brain senses that food might be limited (for example, by interpreting environmental cues previously associated with food scarcity) it may act early to conserve energy and adjust immune function in advance.

If these findings are confirmed in humans, this new data could, in future, have real-world implications for diseases where the immune system becomes overactive – such as , , and wasting syndrome in .

This is of further relevance for metabolic and eating disorders, such as or . Not only are these disorders often accompanied by chronic inflammation or immune-related complications, they can also alter how are computed in the brain.

And, if the brain is able to help dial the immune system up or down, it may be possible to develop new brain-targeted approaches to aid current immuno-modulatory therapies.

Still, there’s much we don’t know. We need more studies investigating how this mechanism works in humans. These studies could prove challenging, as it isn’t possible yet to selectively activate specific neurons in the human brain with the same precision we can in experimental models.

Interestingly, more than a century ago a Soviet psychiatrist, A. Tapilsky, conducted an unusual experiment where he used hypnosis to suggest feelings of hunger or fullness to patients. Remarkably, immune cell counts increased when patients were told they were full and decreased when they were told they were hungry.

These early observations hinted at a powerful connection between the mind and body, well ahead of today’s scientific understanding and are eerily prescient of our current ability to use powerful genetic tools to artificially generate internal sensations like hunger or fullness in animal models.

What’s clear is that the brain’s view of the body’s energy needs can shape the immune system – sometimes even before the body itself has caught up. This raises new questions about how conditions such as stress, eating disorders and even learned associations with food scarcity might drive inflammation and disease.The Conversation

, Senior Lecturer, Division of Diabetes, Endocrinology & Gastroenterology, and , Postdoctoral Researcher, Physiology and Metabolism,

This article is republished from under a Creative Commons license. Read the .

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Mon, 07 Apr 2025 08:16:14 +0100 https://content.presspage.com/uploads/1369/f20df8ef-7609-494c-bc22-477ee9ca4155/500_beautiful-asian-woman-smiling-biting-450w-515753200.jpg?10000 https://content.presspage.com/uploads/1369/f20df8ef-7609-494c-bc22-477ee9ca4155/beautiful-asian-woman-smiling-biting-450w-515753200.jpg?10000
Professor Cinzia Casiraghi appointed as Chief Scientific Officer at the GEIC /about/news/professor-cinzia-casiraghi-appointed-as-chief-scientific-officer-at-the-geic/ /about/news/professor-cinzia-casiraghi-appointed-as-chief-scientific-officer-at-the-geic/693042Professor Cinzia Casiraghi has been appointed as Chief Scientific Officer (CSO) at the Graphene Engineering Innovation Centre (GEIC), bringing with her more than two decades of pioneering research experience in graphene and 2D materials.

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Professor Cinzia Casiraghi has been appointed as Chief Scientific Officer (CSO) at the Graphene Engineering Innovation Centre (GEIC), bringing with her more than two decades of pioneering research experience in graphene and 2D materials.

Since the early 2000s, Professor Casiraghi has been at the forefront of the graphene journey. From identifying the optical fingerprint of graphene to engineering ink-jet printable 2D materials for use in electronics and biomedical applications, her work has paved the way for the development of functional, scalable applications that are now becoming reality across industries.

Casiraghi’s appointment marks a new chapter for the GEIC, which sits at the heart of the Graphene@Manchester ecosystem. As CSO, she will provide strategic scientific leadership to strengthen the Centre’s role as a world-leading facility for the translation of 2D materials research into commercial products and technologies. 

She will play a key role in connecting academic expertise with industrial needs, supporting collaborative research at higher Technology Readiness Levels (TRLs), and steering the scientific direction of GEIC projects.   

Her research group at ֱ has led groundbreaking work in Raman spectroscopy of carbon-based nanomaterials, and 2D material ink formulation, with an emphasis on industry-funded projects. Her contributions to printable electronics, ranging from photodetectors, transistors and memories printed onto low-cost and biodegradable substrates, such as paper, have significantly advanced the field. Casiraghi is also a prominent advocate for cross-disciplinary research, building bridges between chemistry, physics, materials science, and engineering.

Professor Casiraghi said:

“It is an exciting time for 2D materials. I am honoured to take on the role of Chief Scientific Officer at the GEIC. For the past 20 years, I have been dedicated to graphene and 2D materials research, witnessing remarkable progress along this journey. Two decades ago, I was looking at tiny graphene flakes, produced by mechanical exfoliation, with the aim to identify their optical fingerprint.

“Today, academics and companies regularly use this framework to identify graphene. Today, we have graphene and 2D material inks that can be printed onto paper and plastic to create functional devices, or can be combined with other materials to enhance specific properties. Today, we have well-established methods for large-area deposition of graphene and 2D materials, paving the way for their integration into next-generation electronics.

“I look forward to driving innovation, advancing our research capabilities, and working alongside the team at the GEIC and the academic community to develop cutting-edge solutions. By fostering collaboration between academia and industry, we aim to demonstrate the value of 2D materials and their transformative potential.”

James Baker, CEO of Graphene@Manchester, said:
“Cinzia has been a driving force in the field of graphene and 2D materials research for over two decades, and her appointment as Chief Scientific Officer marks a significant development opportunity for the GEIC. Her depth of expertise, combined with a passion for innovation and collaboration, will ensure we continue to bridge the gap between fundamental science and real-world application.

“As the GEIC evolves to meet the challenges of a fast-moving innovation landscape, Cinzia’s leadership will help accelerate our mission to deliver sustainable, scalable technologies that make a meaningful impact across industry sectors.”

As CSO, Professor Casiraghi will work across the GEIC’s ecosystem — including academic departments, the National Graphene Institute (NGI), and the wider university research community — to ensure alignment of scientific vision with industrial ambition. She will lead a team of Theme Leads, drawn from disciplines including materials science and physics, to guide project direction, advise on research outcomes, and lower the barrier between industry and academia.

The role also includes high-level engagement with strategic partners and national innovation stakeholders, helping to position the GEIC as a key player in addressing global challenges around clean growth, mobility, and sustainable development. Casiraghi will support the evaluation of major project proposals, mentor scientific staff, and champion excellence in research infrastructure, collaboration, and impact.

Professor Casiraghi has held academic roles at ֱ since 2010 and currently serves as Chair of Nanoscience and Head of Materials Chemistry in the Department of Chemistry. She previously held research fellowships in Berlin and Cambridge and holds a PhD in Electrical Engineering from the University of Cambridge.

With this appointment, ֱ continues to reinforce its commitment to translating cutting-edge research into real-world impact, supporting the advancement of graphene and 2D materials through collaborative innovation and industrial engagement.

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Fri, 04 Apr 2025 16:04:00 +0100 https://content.presspage.com/uploads/1369/5e1fe4e0-7e7f-4b2a-82e3-09c5f98bc1b6/500_untitleddesign6.png?10000 https://content.presspage.com/uploads/1369/5e1fe4e0-7e7f-4b2a-82e3-09c5f98bc1b6/untitleddesign6.png?10000
Scientists discover deep-sea microplastic hotspots driven by fast-moving underwater avalanches /about/news/scientists-discover-deep-sea-microplastic-hotspots-driven-by-fast-moving-underwater-avalanches/ /about/news/scientists-discover-deep-sea-microplastic-hotspots-driven-by-fast-moving-underwater-avalanches/692887Fast-moving underwater avalanches, known as turbidity currents, are responsible for transporting vast quantities of microplastics into the deep sea, according to new research published today.

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Fast-moving underwater avalanches, known as turbidity currents, are responsible for transporting vast quantities of microplastics into the deep sea, according to new research published today.

The findings, published in the journal ,  show that these powerful flows could be capable of traveling at speeds of up to eight meters per second, carrying plastic waste from the continental shelf to depths of more than 3,200 meters.

Over 10 million tonnes of plastic waste enter the oceans each year. While striking images of floating debris have driven efforts to curb pollution, this visible waste accounts for less than 1% of the total. The missing 99% – primarily made up of fibres from textiles and clothing – is instead sinking into the deep ocean.

Scientists have long suspected that turbidity currents play a major role in distributing microplastics across the seafloor – ֱ were among the first to demonstrate this through their research on ‘Microplastic Hotspots’ in the Tyrrhenian Sea, published in the journal . However, until now, the actual process had not been observed or recorded in a real-world setting.

The latest study conducted by ֱ, the National Oceanography Centre (UK), the University of Leeds (UK), and the Royal Netherlands Institute for Sea Research provides the first field evidence showing the process.

The findings pose a significant threat to marine ecosystems and highlight the urgent need for stronger pollution controls.

Dr Peng Chen, lead author on the study at ֱ, said “Microplastics on their own can be toxic to deep-sea life, but they also act as ‘carriers’ transferring other harmful pollutants such as PFAS ‘forever chemicals’ and heavy metals, which makes them an environmental ‘multistressor’ which can affect the entire food chain.”

The research focused on Whittard Canyon in the Celtic Sea, a land-detached canyon over 300 km from the shore. By combining in-situ monitoring and direct seabed sampling, the team were able to witness a turbidity current in action, moving a huge plume of sediment at over 2.5 metres per second at over 1.5 km water depth. The samples directly from the flow revealed that these powerful currents were not only carrying just sand and mud, but a significant quantity of microplastic fragments and microfibres.

Further analysis found that the microplastics on the seafloor are mainly comprised of fibres from textiles and clothing, which are not effectively filtered out in domestic wastewater treatment plants and easily enter rivers and oceans.

, Geologist and Environmental Scientist at ֱ, who designed and led the research, said: “These turbidity currents carry the nutrients and oxygen that are vital to sustain deep-sea life, so it is shocking that the same currents are also carrying these tiny plastic particles.

“These biodiversity hotspots are now co-located with microplastic hotspots, which could pose serious risks to deep-sea organisms.

“We hope this new understanding will support mitigations strategies going forward.”

Dr Mike Clare of the , who was a co-lead on the research, added: “Our study has shown how detailed studies of seafloor currents can help us to connect microplastic transport pathways in the deep-sea and find the ‘missing’ microplastics. The results highlight the need for policy interventions to limit the future flow of plastics into natural environments and minimise impacts on ocean ecosystems.”

The study team are now focussing on efforts to better understand the effect that microplastics have on marine organisms, for example sea turtles and deep-sea fauna.

This research was published in the journal Environmental Science and Technology.

Full title: Direct evidence that microplastics are transported to the deep sea by turbidity currents

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Fri, 04 Apr 2025 08:00:00 +0100 https://content.presspage.com/uploads/1369/f1f1cfdc-7aed-40e7-9484-acc948502da0/500_pressrelease2.jpg?10000 https://content.presspage.com/uploads/1369/f1f1cfdc-7aed-40e7-9484-acc948502da0/pressrelease2.jpg?10000
New technology reveals volcanic CO2 emissions could be three time higher than anticipated /about/news/new-technology-reveals-volcanic-co2-emissions-could-be-three-time-higher-than-anticipated/ /about/news/new-technology-reveals-volcanic-co2-emissions-could-be-three-time-higher-than-anticipated/692749Estimates of carbon dioxide (CO2) emissions from volcanoes may have been significantly underestimated, according to new research by ֱ.

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Estimates of carbon dioxide (CO2) emissions from volcanoes may have been significantly underestimated, according to new research by ֱ.

Published in the journal, , scientists have developed an advanced sensor that can detect volcanic gases with rapid speed and precision.

Using the sensor mounted on a helicopter, the research team measured emissions at Soufrière Hills Volcano on the Caribbean Island of Montserrat, revealing that the volcano emitted three times more CO2 than earlier studies had estimated.

Scientists typically monitor volcanic emissions by focusing on hot vents, known as fumaroles, which release high concentrations of easily detectable acid gases like sulphur dioxide (SO₂) and hydrogen chloride (HCl). However, many volcanoes also have cooler fumaroles, where water-rich hydrothermal systems on the volcano absorb the acidic gases, making them harder to detect. As a result, CO₂ emissions from these cooler sources are often overlooked, leading to significant underestimations in volcanic gas output.

The new technology exposes those hidden emissions, offering a more accurate quantification of the volcanoes gas output.

The findings also have significant implications for volcano monitoring and eruption forecasting.

, lead researcher from ֱ, said: “Volcanoes play a crucial role in the Earth's carbon cycle, releasing CO₂ into the atmosphere, so understanding the emissions is crucial for understanding its impact on our climate. Our findings demonstrate the importance of fast sampling rates and high precision sensors, capable of detecting large contributions of cooler CO2-rich gas.

“However, it’s also important to realise that despite our findings that CO2 emissions could be around three times higher than we expected for volcanoes capped by hydrothermal systems, volcanoes still contribute less than 5% of global CO2 emissions, far less than human activities such as fossil fuel combustion and deforestation.”

and co-author, added: “Development of high-sensitivity high-frequency magmatic gas instruments opens up a new frontier in volcanological science and volcano monitoring. This work demonstrates the new discoveries which await us. By capturing a more complete picture of volcanic gas emissions, we can gain deeper insights into magma movement, observe potential signs of impending eruptions and signs that an ongoing eruption might be ending. For the people living near active volcanoes, such advancements could enhance early warning systems and improve safety measures.”

The research was carried out in collaboration with Montserrat Volcano Observatory and the National Institute of Optics, Firenze, Italy. Now, the study team are searching for funding to make this instrument suitable for unmanned aerial vehicle platforms, opening up new opportunities for performing delicate gas measurements in challenging and hazardous environments.  

This research has been published in the journal Scientific Advances. 

Full title: Quantification of Low-Temperature Gas Emissions Reveals CO₂ Flux Underestimates at Soufrière Hills Volcano, Montserrat.

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